Description
Taylor & Francis Axonal Regeneration in the Central Nervous System 2000 Edition by Nicholas A Ingoglia, Marion Murray
Summarizing a review of research into factors that regulate, stimulate, and prevent regeneration in the central nervous system (CNS), this comprehensive reference progresses further into answering and resolving neuron capacity for axon regeneration in the mammalian CNS. Axonal Regeneration in the Central Nervous Systemanalyzes axonal regeneration, reinnervation, and functional recovery in lower vertebrates examines the correlation between developmental age and the ability to regenerate considers mammalian neuron responses at the cell body, site of injury, and in the distal nerve, including apoptic cell death, and inflammatory and glial responses to injury reviews genomic responses to axotomy with a comparative description of transcribed genes from successfully regenerating neurons and neurons incapable of regrowth discusses how growing axons may induce the expression of genes in glia/Schwann cells following axotomy and regeneration describes the use of gene therapy to deliver trophic and survival factors to injured neurons explores the hospitable environments of the peripheral nerve, olfactory ensheathing cells, and fetal cell transplants for regeneration discusses results from applications of fetal CNS tissue to human spinal cord injuries and much more! Table of contents : - Axon Regeneration in Lower VertebratesMolecular Determinants of Retinal Axon Pathfinding in Fish, C. Stuermer and C. LeppertAxonal Regeneration in the Primary Visual Pathway of Goldfish and Rats,L. Benowitz, S. Leon, R. Tabibiazar, Y. Jing and N. IrwinRegeneration of Axons in the CNS of Amphibians and Reptiles, L. BeazleyAxonal and Synaptic Regeneration by Salamander Photoreceptors,E. Townes-Anderson and M. Nachman-ClewnerRegeneration as a Function of Developmental AgeCues from Developmental Models of Spinal Cord Regeneration for the Repair of the Injured Adult CNS,J. D. SteevesIntrinsic Control of Regeneration and the Loss of Regenerative Ability in Development,J. Fawcett Regeneration Following Axotomy of Mammalian NeuronsThe Cell Body Response to AxotomyApoptotic Cell Death Following Axotomy,P. Chaudhary and S. C. SharmaGene Expression in Axotomized Neurons: Identifying the Intrinsic Determinants of Axonal Growth,K. J. L. Fernandes and W. TetzlaffA-Fiber Central Sprouting After Peripheral Nerve Injury - New Pathways for Pain?,R. J. Mannion and C. J. WoolfResponse at the Site of Injury and in Degenerating/Regenerating NervesInflammatory Response Following Nerve Injury, G. Raivich and G. W. KreutzbergGlial Response to Injury,S. Hirsch and M. BahrAxonal Sealing Following Injury,G. D. Bittner and H. M. FishmanN-Terminal Arginylation of Proteins and Transcellular Transfer of Small Molecules in Regenerating Nerves,N. Ingoglia and N. ZhangGene Expression in Degenerating/Regenerating Nerves,C. Gillen Factors that Influence Axonal OutgrowthInhibition of Axonal Growth by the Myelin-Associated Inhibitory Proteins NI-35/NI-250/Nogo-AM. E. Schwab Inhibition of Axonal Growth by Myelin Associated Glycoprotein,S. David and L. McKerracherAxonal Growth in a Glial Environment,G. RaismanCell Surface and Extracellular Molecules that Promote or Inhibit Axonal Growth,M. GrumetStrategies for Stimulating Axonal Growth Following CNS InjuryNeuroprotection from Cell Death Following Axotomy,B. T. Himes and A. TesslerThe Use of Peripheral Nerve Transplants to Enhance Axonal Regeneration in CNS Neurons,K. F. So and H.K. YipTransplantation of Schwann Cells and Ensheathing Glia to Improve Regeneration in Adult Spinal Cord,G. Plant, A. Ramon-Cueto, and M. B. BungeGene Therapy Strategies,I. Fischer and Y.LiuSpinal Cord Injury and Fetal CNS Tissue Transplantation: An Initial Bench-to-Bedside Translational Research Experience,P. J. Reier, F. J. Thompson, R. G. Fessler, D. K. Anderson, and E. D. Wirth IIITherapies to Promote CNS Repair,M. MurrayPerspectiveTreatment of Degenerative Disorders of the Nervous System: from Helpless Descriptive Categorization to Rational Therapeutic Approaches,H. Thoenen