Description
Taylor & Francis Ltd Chronic Obstructive Pulmonary Disease Exacerbations 2008 Edition by Jadwiga A. Wedzicha, Fernando J. Martinez
Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbations:is formatted into separate sections covering imaging diagnosis and treatment, making this text practical and easy-to-useexamines current and breakthrough pharmacologic and non-pharmacologic treatmentsincludes COPD-causing exacerbations such as viral and bacterial infectionsdiscusses the negative environmental factors relating to COPD PART I INTRODUCTIONDefinitions and severity of COPD exacerbations: Stephen Rennard and Nancy Kline LeidyEpidemiology of COPD exacerbations: David ManninoDifferential diagnosis of COPD exacerbations: Peter Calverley PART II MECHANISMS AND PATHOPHYSIOLOGYSymptom changes at exacerbations: Terry Seemungal Airway pathology at exacerbations: Marina Saetta Airway and systemic inflammatory markers at exacerbation: John Hurst Physiological changes at exacerbations: Dennis O'Donnell and Chris Parker Systemic consequences of COPD exacerbations: Emiel WoutersMechanisms of respiratory failure at exacerbation: Roberto Rodriguez Roisin Role of respiratory viral infection at exacerbation: Wisia Wedzicha and Jennie Quint Do airway bacteria cause COPD exacerbations: Sanjay Sethi Interactions of airway pathogens and inflammatory processes: Alberto PapiRole of co-morbidity at COPD exacerbations: Bill MacNee, John Maclay and David McAllisterEnvironmental causes of exacerbations: David Hui and Fanny KoMechanisms and pathophysiological changes in alpha-1 AT deficiency exacerbations: Rob StockleyExperimental models of COPD exacerbations: Jeff CurtisComparison of asthma and COPD exacerbations: Sebastian JohnstonPART III IMPACT OF EXACERBATIONSExacerbations and health status: Paul JonesRisk factors for hospital admission: Judith Garcia Aymerich Effect of exacerbations on disease progression and mortality: Gavin DonaldsonHealth economic consequences of COPD exacerbations: Marc MiravitllesPART IV MANAGEMENT OF THE ACUTE EXACERBATIONUse of bronchodilators and mucolytics at COPD exacerbations: Marc DecramerCorticosteroids in the management of acute exacerbations: Denis Niewoehner Antibiotic therapy at COPD exacerbations: Rob WilsonNon invasive ventilatory support: Mark Elliott and Stanley MillerInvasive ventilation and weaning at COPD exacerbation: Antonio AnzuetoOxygen therapy at exacerbations: Tony Davison and Luke WilsonEnd of life issues and COPD exacerbations: Anita Simonds Novel models of care for COPD exacerbations: Martyn PartridgePhysiotherapy airway clearance at exacerbation: Christine Mikelsons and Rachel Garrod COPD exacerbation and pulmonary rehabilitation: Mike Polkey and William MannPART V PREVENTION OF COPD EXACERBATIONPharmacological prevention of COPD exacerbations: Leo Fabbri Early intervention and self-management in exacerbation prevention: Jean BourbeauImmunological interventions: Phillip PooleHome mechanical ventilation and oxygen therapy: Gerry Criner and Nat MarchettiPART VI ISSUES FOR STUDIES OF COPD EXACERBATIONSDesign of trials for COPD exacerbations: Fernando Martinez Statistical considerations for COPD exacerbation trials: Shawn Aaron Future development in COPD exacerbations: Peter Barnes