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Clinical Trials in Rheumatoid Arthritis and Osteoarthritis 2008 Edition at Meripustak

Clinical Trials in Rheumatoid Arthritis and Osteoarthritis 2008 Edition by David M. Reid, Colin G. Miller , Springer

Books from same Author: David M. Reid, Colin G. Miller

Books from same Publisher: Springer

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  • General Information  
    Author(s)David M. Reid, Colin G. Miller
    PublisherSpringer
    ISBN9781852338749
    Pages328
    BindingPaperback
    LanguageEnglish
    Publish YearMay 2008

    Description

    Springer Clinical Trials in Rheumatoid Arthritis and Osteoarthritis 2008 Edition by David M. Reid, Colin G. Miller

    Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these increasingly complex diseases.In the last several years a new classes of biologic agents have emerged and changed the treatment paradigm for patients, not only with classically defined rheumatoid arthritis, but also with other related diseases such as ankylosing spondylitis and psoriatic arthritis. Furthermore, osteoarthritis is a major disease state that is often treated by the rheumatologist, but is one where patient management programs are currently limited with a need for new therapeutic approaches.In both inflammatory and non-inflammatory arthritic conditions, clinical trials have become both large and complex due to the nature of the diseases, with ever-challenging new surrogate end-points being employed. Topics covered in this title will therefore include study design, clinical endpoints, technical issues, data collection, use of centralized medical image reading facilities and biochemical marker laboratories, as well as data analysis and future therapies. This book takes the user through the process step-by-step from start to finish, also providing a background on the regulatory guidelines, ethical implications, endpoints, and current therapies.