Description
Taylor & Francis Ltd Copper Amine Oxidases 2009 Edition by Giovanni Floris, Bruno Mondovi
Although the amount of research on copper amine oxidases has grown rapidly and substantially in the past decade, the field unfortunately suffers from lack of cohesion and significant confusion surrounds aspects as simple as confirmation of enzyme identities. This book describes the structure of the enzymes, the role of copper, and of the unusual cofactor 6-hydroxydopa quinine derived from a posttranslational modification of a tyrosine residue. It also covers the differences of between AOs from bacteria, plants, and mammals. Finally, the text examines the importance of this ubiquitous class of enzymes in physiology and in metabolism of biogenic amines. History, F. BuffoniNomenclature and Potential Functions of Copper Amine Oxidases, S. Boyce, K. F. Tipton, M. I. O'Sullivan, G. P. Davey, M. Motherway Gildea, A. G. McDonald, A. Olivieri, and J. O'SullivanCofactors of Amine Oxidases: Copper Ion and Its Substitution and the 2, 4, 5-Trihydroxylphenylalanine Quinone, S. Suzuki, T. Okajima, K. Tanizawa, and M. MureCopper Amine Oxidases from Plants, R. Medda, A. Bellelli, P. Pec, R. Federico, A.Cona, and G. FlorisSoluble Copper Amine Oxidases from Mammals, P. Pietrangeli, L. Morpurgo, B. Mondovi, M. L. Di Paolo, and A. RigoMembrane-Bound Copper Amine Oxidases, A. HoltCopper Amine Oxidase Genes, I. Frebort and H. G. SchwelbergerMechanism of TPQ Biogenesis in Prokaryotic Copper Amine Oxidase, T. Okajima and K.TanizawaCopper Amine Oxidase Crystal Structures, J. Mitchell Guss, G. Zanotti, and T. A. SalminenPlasma Amine Oxidases in Various Clinical Conditions and in Apoptosis, F. Boomsma, A. H. van den Meiracker, and A. ToninelloCopper Amine Oxidases in Intestine Diseases, W. Agnieszka Fogel, E. Toporowska-Kowalska, and A. StasiakCopper Amine Oxidases in Adipose Tissue-Related Disorders, C. CarpeneCopper Amine Oxidases in Adhesion Molecules in Renal Pathology and in Alzheimer's Disease and VAP-1 in Leukocyte Migration, P. Boor, M. Unzeta, M. Salmi, and S. JalkanenInhibitors of Copper Amine Oxidases: Past, Present, and Future, M. Sebela and L. M. SayrePharmacological Applications of Copper Amine Oxidases, E. Masini and L. RaimondiCopper Amine Oxidases as Antioxidant and Cardioprotective Agents, M. Alexandru Mateescu and R. NadeauBiotechnological Aspects of Copper Amine Oxidases, R. StevanatoConcluding Remarks, D. M. DooleyReferences