DNA Repair Disorders 1st Edition 2019 at Meripustak

DNA Repair Disorders 1st Edition 2019

Books from same Author: Chikako Nishigori

Books from same Publisher: Springer

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  • General Information  
    Author(s)Chikako Nishigori
    PublisherSpringer
    Edition1st
    ISBN9789811067211
    Pages221
    BindingHardcover
    LanguageEnglish
    Publish YearJune 2019

    Description

    Springer DNA Repair Disorders 1st Edition 2019 by Chikako Nishigori

    This book focuses on the clinical aspects of DNA repair disorders. Nucleotide excision repair is an important pathway for humans, as it is involved in biologically fundamental functions. This work presents clinical features together with the pathogenesis of DNA repair disorders such as Xertoderma Pigmentosum (XP). Studies on animal models are included as well. 

    Clinical feature characteristics of each clinical subtype of XP are depicted according to the genotype, giving accurate and detailed information about the clinical features in terms of gene alterations, change of protein structure, and dysfunction in some of the repair pathways. This book is unique in that it provides detailed information on clinical features from more than 100 patients with XP-A, which is characterized by very severe manifestation of skin photosensitivity and neurological dysfunction. It will give readers important knowledge for understanding the concept and molecular mechanisms of DNA repair disorders. It also describes how to treat and care for patients with XP based on vast experience in clinical practice.