Description
Taylor & Francis Efficacy of Myocardial Infarction Therapy An Evaluation of Clinical Trials Evidence 1999 Edition by Valentin Fuster
In this unique reference, nearly 50 principal investigators of major clinical trials of myocardial infarction (MI) therapy explain how their work has contributed to the current standard of care. Includes the work of researchers at an impressive range of distinguished institutions worldwide! Providing the basis for treatment guidelines, Efficacy of Myocardial Infarction Therapyexamines clinical trials that have established the efficacy of particular therapies, including acute coronary reperfusion; the use of aspirin, beta blockers, and ACE inhibitors; and the reduction of blood cholesterol reviews trials that have cast doubt on the efficacy of other therapies, including the early and late use of calcium channel blockers, and the routine use of heparin, nitroglycerin, and magnesium deals with alternative overall strategies for myocardial infarction care, such as invasive versus conservative management and the interplay of thrombolysis and PTCA and more! Including over 1400 references, tables, drawings, and photographs Efficacy of Myocardial Infarction Therapy benefits cardiologists, internists, family practitioners, fellows, residents, and graduate and medical school students in these disciplines. Table of contents : - THERAPIES WITH ESTABLISHED EFFICACY Thrombolysis GISSI-1, Gianni Tognoni and Aldo P. MaggioniISIS-2, Peter SleightASSET, Robert G. WilcoxISIS-3, Peter SleightGUSTO-1, Maran Thamilarasan and Eric J. TopolLATE, John R. HamptonEMERAS, Ernesto Paolasso and Rafael DiazInsights from the GUSTO Trials on Studies of Coronary Reperfusion, Robert M. CaliffPrimary PTCA The Mayo Clinic Primary PTCA Trial, David R. Holmes, Jr., and R. J. GibbonsThe Zwolle Primary PTCA Trial, Felix ZijlstraGUSTO-IIB, Neeraj Jolly and Stephen G. EllisAspirin ISIS-2, Peter SleightBeta-Blockers: Early Use ISIS-1, Peter SleightThe Goeteborg Metoprolol Trial, Ake HjalmarsonMIAMI, Ake HjalmarsonTIMI-IIB, Robert Roberts and Eugene BraunwaldBeta-Blockers: Delayed Use The Norwegian Timolol Study, Terje R. PedersonBHAT, Robert P. Byington ACE Inhibitors: Early Use CONSENSUS-II, John Kjekshus, Karl Swedberg, and Steven M. SnappinGISSI-3, Gianni Tognoni and Aldo P. MaggioniISIS-4, Peter SleightSMILE, Claudio Borghi and Ettore AmbrosiniACE Inhibitors: Delayed Use SAVE, Marc A. Pfeffer and Eugene BraunwaldAIRE, Alistair S. Hall and Stephen G. BallTRACE, Lars Kober and Christian Torp-PedersenCholesterol ReductionCARE, David T. NashTHERAPIES WITHOUT ESTABLISHED EFFICACY Calcium Channel Blockers: Early Use DAVIT-1, Jorgen Fischer HansenTRENT, Robert G. WilcoxCalcium Channel Blockers: Delayed UseMDPIT, Robert E. GoldsteinSPRINT, Solomon BeharDAVIT-2, Jorgen Fischer HansenHeparin GISSI-2, Gianni Tognoni and Aldo P. MaggioniISIS-3, Peter SleightNitrates GISSI3, Gianni Tognoni and Aldo P. MaggioniISIS-4, Peter SleightMagnesium LIMIT-2, Kent L. WoodsISIS-4, Peter SleightsALTERNATIVE STRATEGIES IN ACUTE MYOCARDIAL INFARCTION Invasive or Conservative Management TIMI-IIB, Christopher P. Cannon and Eugene BraunwaldSWIFT, David P. de BonoThrombolysis and PTCA TIMI-IIA, Robert P. Giugliano and Eugene BraunwaldTAMI and PAMI, William W. O'Neill