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  • General Information  
    Author(s)Mohit Bhandari
    Publish YearOctober 2021


    Wiley Evidencebased Orthopedics 2021 Edition by Mohit Bhandari

    Evidence-Based Orthopedics is an up-to-date review of the best evidence for the diagnosis, management, and treatment of orthopedic conditions. Covering orthopedic surgery as well as pre- and post-operative complications, this comprehensive guide provides recommendations for implementing evidence-based practice in the clinical setting. Chapters written by leading clinicians and researchers in the field are supported by tables of evidence that summarize systematic reviews and randomized controlled trials. In areas where evidence is insufficient to recommend a practice, summaries of the available research are provided to assist in decision-making.

    This fully revised new edition reflects the most recent evidence using the approved evidence-based medicine (EBM) guidelines and methodology. The text now places greater emphasis on GRADE—a transparent framework for developing and presenting summaries of evidence—to allow readers to easily evaluate the quality of evidence and the strength of recommendations. The second edition offers a streamlined presentation and an improved standardized format emphasizing how evidence in each chapter directly affects clinical decisions. Incorporating a vast amount of new evidence, Evidence-Based Orthopedics:

    Features thoroughly revised and updated content, including a new chapter on pediatric orthopedics and new X-ray images
    Provides the evidence base for orthopedic surgery as well as pediatric orthopedics and orthopedic conditions requiring medical treatment
    Covers the different methods for most orthopedic surgical procedures, such as hip replacements, arthroscopy, and knee replacements
    Helps surgeons and orthopedic specialists achieve a uniform optimum standard through a condition-based approach
    Aligns with internationally accepted guidelines and best health economic principles Evidence-Based Orthopedics is an invaluable resource for orthopedic specialists, surgeons, trauma surgeons, trainees, and medical students.


    MOHIT BHANDARI, MD, PHD, FRCSC, is Professor of Surgery in the Division of Orthopedic Surgery at McMaster University, Ontario, Canada. He is a University Scholar, holds a Canada Research Chair in Evidence-Based Orthopedics, serves as Associate Chair-Research in the Department of Surgery, and was inducted as a member of the Order of Canada. Dr Bhandari has been acknowledged as one of the top 10 most cited orthopedic fracture surgeons in the world. He conducts major multinational, transformative randomized clinical trials, publishes actively in the top medical journals, lectures to thousands around the world, and edits several major textbooks. He is Editor-in-Chief of OrthoEvidence, an online source for high quality and timely evidence-based orthopedic summaries.


    Contributors, xv

    Foreword, xxix

    Preface, xxxi

    Abbreviations, xxxiii

    Section I Methodology of Evidence-Based Orthopedics

    1 Principles of Evidence-Based Orthopedics, 3
    Niek van der Hoek MD and Paul Tornetta III MD

    2 Hierarchy of Evidence and Common Study Designs, 7
    Annie George BHSc, Ydo V. Kleinlugtenbelt MD PhD, and Kim Madden PhD

    3 Systematic Reviews and Meta-Analyses, 11
    Joseph T. Patterson MD and Saam Morshed MD PhD MPH

    4 Healthcare Recommendations: Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) Approach, 19
    Mark Phillips BSc PhD, Cand

    5 Outcomes and Their Interpretations, 25
    Leah Gitajn MD

    6 Value-Based Orthopedics, 31
    Nathan N. O'Hara MHA and Daniel Mwayafu MBChB MMed

    Section II Orthopedic Medicine

    7 Critical Issues in Osteoporosis Management, 39
    Matthew Wong-Pack BHSc MD (Cand), Kyra Cummings, Arthur Lau MD FRCPC, and Jonathan D. Adachi MD FRCPC

    8 Venous Thromboembolic Events, 51
    Ernest Kwek MBBS FRCS(Ed) and Richard E. Buckley MD FRCSC

    9 Blood Transfusion, 55
    Seper Ekhtiari MD MSc, David W. Sanders MD FRCSC, and Jeffrey L. Carson MD

    10 Wound Infections, 59
    Mark D. Hasenauer MD, Michael D. Hunter MD, Kyle J. Jeray MD, and Atul F. Kamath MD

    11 Smoking Cessation, 65
    Paul E. Matuszewski MD, David Zuelzer MD, and Robert V. O'Toole MD

    12 Perioperative Medical Management, 71
    Jennifer Muniak MD, Susan M. Friedman MD MPH, Joseph A. Nicholas MD MPH, and Daniel A. Mendelson MD MSc

    13 Orthobiologics, 75
    John A. Buza III MD and Thomas A. Einhorn MD

    14 Intimate Partner Violence, 83
    Sheila Sprague PhD, Taryn Scott MSW, Erika Arseneau MSc, Prism Schneider MD FRCSC, Andrew Furey MD FRCSC, Rudolf Poolman MD PhD, Emil Schemitsch MD, and Mohit Bhandari MD PhD

    15 Pain Management in Orthopedic Surgery, 91
    Vishal Uppal MD FRCA and Harsha Shanthanna MD PhD

    16 Post-Traumatic Stress Disorder and Depression, 99
    Basem Attum MD and William Obremsky

    17 Nutrition and Supplements in Orthopedic Care, 105
    Martí Bernaus MD, Brad Petrisor MD MSc, Sofia Bzovsky MSc, and Sheila Sprague PhD

    Section III Joint Reconstruction

    III.I Hip and Knee

    18 Outpatient Total Joint Arthroplasty, 113
    Michael Pollock BSc MSc and Brent Lanting MD

    19 Hip Preservation, 117
    Ahmed El-Bakoury MBBS PhD, Asif A. H. Parkar MBBS, and James N. Powell MD

    20 The Direct Anterior Approach, 123
    Thomas J. Wood MD and Brent Lanting MD MSc

    21 Computer Navigation in Total Hip Arthroplasty, 129
    Aamer Malik MD PhD and Lawrence Dorr MD

    22 Highly Crosslinked Polyethylene in Total Hip Arthroplasty, 135
    Glen Richardson MD MSc FRCSC and Michael J. Dunbar MD PhD FRCSC

    23 Hip Resurfacing, 141
    Adam Hart MD MASc, Nikolaos Davarinos MD MSc, and John Antoniou MD PhD

    24 Metal-on-Metal Hip Arthroplasty, 147
    Oliver Marin-Peña MD, Olga Pidgaiska MD, and PedroReis-Campos

    25 Ceramic in Total Hip Arthroplasty, 153
    Peter M. Lewis MB BCh FRCS(Orth) and James P. Waddell MD FRCSC

    26 Cement in Total Hip Arthroplasty, 161
    Jorge H. Nuñez MD, Tony Fraguas MD, Ernesto Guerra-Farfán MD, and Diego Collado MD

    27 Head Size in Total Hip Arthroplasty, 167
    Francesc Angles MD, Jorge H. Nuñez MD, and Pablo Castillón MD

    28 Dual Mobility in Total Hip Arthroplasty, 173
    Iñaki Mimendia MD, Maria Jurado MD, Ernesto Guerra-Farfán MD, and Victor Barro MD PhD

    29 Trunnionosis, 179
    Christopher Del Balso MBBS MSc, Emil Schemitsch MD, and Brent Lanting MD MSc

    30 Periprosthetic Hip Fractures, 185
    Lisa C. Howard MD, Bas A. Masri MD, Don S. Garbuz MD, and Clive P. Duncan MD

    31 The Infected Total Hip Arthroplasty, 191
    Sebastián A. León MD, Xin Y. Mei MD, and Paul R. Kuzyk MD MASc

    32 The Painful Total Hip Arthroplasty, 199
    Asif A. H. Parkar MBBS, Ahmed El-Bakoury MBBS PhD, and James N. Powell MD

    33 Revision of the Femoral Component, 205
    Lisa C. Howard MD, Bas A. Masri MD, Don S. Garbuz MD, and Clive P. Duncan MD

    34 Revision of the Acetabular Component, 213
    Nikolaos Davarinos MD MSc, Adam Hart MDCM MASc, and John Antoniou MD PhD

    35 Antibiotic Cement in Total Knee Arthroplasty, 221
    Stephen M. Petis MD MSc FRCSC and Steven J. MacDonald MD FRCSC

    36 Unicompartmental Knee Arthroplasty and Patellofemoral Resurfacing Arthroplasty, 225
    Waleed Albishi MBBS, Paul Jamieson MD, IvanKamikovski MD, and Geoffrey Dervin MD

    37 Cemented versus Uncemented Fixation in Total Knee Arthroplasty, 231
    Thomas Turgeon MD FRCSC

    38 Cruciate Retaining versus Posterior Stabilized Total Knee Arthroplasty, 237
    Michael G. Zywiel MD MSc FRCSC and Sarah Ward MD MLA FRCSC

    39 Patellar Resurfacing in Total Knee Arthroplasty, 243
    Michael G. Zywiel MD MSc FRCSC, Rajiv Gandhi MD MSc FRCSC, and Nizar N. Mahomed MD ScD FRCSC

    40 Mechanical versus Kinematic Alignment in Total Knee Arthroplasty, 249
    Pascal-André Vendittoli MD MSc, William Blakeney MBBS MSc MS FRACS, Charles Rivière, and Gene Dossett

    41 Ligament Balancing in Total Knee Arthroplasty, 253
    Pascal-André Vendittoli MD MSc, Jihad Matta MD, Christophe Fornasieri MD, and William Blakeney MBBS MSc MS FRACS

    42 Robotics in Total Knee Arthroplasty, 259
    Seper Ekhtiari MD MSc, Vickas Khanna MD, and Anthony Adili MD

    43 Patient-Specific Instrumentation in Total Knee Arthroplasty, 265
    Seper Ekhtiari MD MSc, Luc Rubinger MD, Vickas Khanna MD, and Anthony Adili MD

    44 Metal Allergy in Total Knee Arthroplasty, 269
    Amit Atrey MD MSc FRCSC

    45 Perioperative Management in Total Knee Arthroplasty, 275
    Sebastian M. Klim MD and Mathias Glehr MD

    46 Arthrofibrosis following Total Knee Arthroplasty, 279
    Samuel T. Walters MBBS, Saket Tibrewal MBBS, and Jakob van Oldenrijk MD PhD

    47 High-Flexion Implants in Total Knee Arthroplasty, 285
    Thomas J. Wood MD FRCSC and Douglas D. R. Naudie MD FRCSC

    48 Venous Thromboembolism in Total Knee Arthroplasty, 289
    Harman Chaudhry MD MSc and Mitch Winemaker MD FRCSC

    49 Highly Cross-Linked Polyethylene in Total Knee Arthroplasty, 295
    Pascal-André Vendittoli MD MSc, William Blakeney MBBS MSc MS FRACS, Ebru Oral, and Orhun Muratoglu

    50 Exposure and Implant Options in Revision Total Knee Arthroplasty, 301
    Felipe Moreira MD, Maria Jurado MD, and Marcelo Casaccia MD

    51 The Painful Total Knee Arthroplasty, 307
    Jason Werle MD FRCSC, Kelly Johnston MD FRCSC, Nicholas Desy MD FRCSC, and Stuart Goodman MD PhD FRCSC

    52 Diagnosing the Infected Total Knee Arthroplasty, 315
    Mina Tohidi MD and John F. Rudan MD

    53 Management of the Infected Total Knee Arthroplasty, 321
    Ewout S. Veltman MD and Dirk Jan F. Moojen MD PhD

    54 Management of the Unstable Total Knee Arthroplasty, 325
    John Esposito MD FRCSC and James L. Howard MD MSc FRCSC

    55 Stem Choices in Revision Total Knee Arthroplasty, 329
    Pablo A. I. Slullitel MD, Gerard M. J. March MD FRCSC, and Paul R. Kim MD FRCSC

    56 Periprosthetic Fractures: Knee, 335
    Jesse Wolfstadt MD MSc FRCSC and Aaron Nauth MD MSc FRCSC

    57 Femoral Bone Defects in Revision Total Knee Arthroplasty, 341
    Adam Katchky MD MSc FRCSC and David J. Backstein MEd MD FRCSC

    58 Management of Structural Defects in Revision Knee Arthroplasty: Tibial Side, 349
    Sebastián León MD, Jennifer Leighton MD FRCSC, Xin Y. Mei MD, and Paul R. Kuzyk MD MASc FRCSC

    59 Patellar Options in Revision Total Knee Arthroplasty, 355
    Jesse Wolfstadt MD MSc FRCSC and Paul Zalzal MASc MD FRCSC

    III.II Shoulder

    60 Implant Design Options in the Treatment of Shoulder Osteoarthritis, 361
    Chad Myeroff MD, Michael Knudsen MD, and Michael D.McKee MD FRCS(C)

    61 Cement in Shoulder Arthroplasty, 369
    Midhat Patel MD and Niloofar Dehghan MD FRCSC

    62 Management of Glenoid Bone Loss, 375
    Diego Soza MD, Montserrat García-Portabella MD, Lledó Batalla MD, and Josep Massons MD PhD

    63 Reverse Total Shoulder Arthroplasty, 381
    Mitchel D. Armstrong MD BMSc FRCSC, Bandar M. Assiry MBBS SB-orth, and Ryan T. Bicknell MD MSc FRCSC

    64 Glenoid Components in Total Shoulder Arthroplasty, 387
    Eric Benson MD, George Athwal MD, and Kenneth Faber MD

    65 Periprosthetic Joint Infection in Shoulder Arthroplasty, 393
    Peter Lapner MD FRCSC, Jay Keener MD, and Thomas Duquin MD

    III.III Foot and Ankle

    66 Ankle Osteoarthritis, 401
    Rosa Busquets MD PhD and Andrea Sallent MD

    67 Osteoarthritis of the 1st Metatarsophalangeal Joint, 407
    Seper Ekhtiari MD MSc and Waleed Kishta MD PhD

    68 Hallux Valgus, 413
    Sebastián Drago Perez MD and Cristian Ortiz Mateluna MD

    69 Cavovarus Foot, 419
    Sebastián Drago Perez MD and Cristian Ortiz Mateluna MD

    Section IV Trauma

    IV.I General Trauma

    70 Damage Control Orthopedics, 425
    Sascha Halvachizadeh MD, Paolo Cinelli PhD, Florin Allemann MD, Philipp Kobbe MD MHBA, and Hans-Christoph Pap MD

    71 Open Fractures, 431
    Michael D. Hunter MD, Mark D. Hasenauer MD, Atul F.Kamath MD, and Kyle J. Jeray MD

    72 The Mangled Extremity, 437
    Tiffany Huynh MD and Ted V. Tufescu MD FRCSC

    73 Acute Compartment Syndrome, 441
    Aurelia Bihari PhD, Christopher Del Balso MBBSMSc FRCSC, and Abdel-Rahman Lawend MD PhD FRCSC

    74 Noninvasive Technologies for Fracture Repair, 447
    Natsumi Saka MD, Yoshinobu Watanabe MD PhD, and Takashi Matsushita MD DSc

    75 Calcium-Based Bone Substitutes, 451
    Ross Leighton BSc MD FRCSC, Kelly Trask BEng MScCCRP, Thomas A. Russell MD, Mohit Bhandari MD MSc, and Richard E. Buckley MD FRCSC

    IV.II Shoulder Girdle and Upper Extremity

    76 Scapula Fractures, 457
    Peter A. Cole MD and Lisa K. Schroder BS MBA

    77 Sternoclavicular Joint, 463
    Annie Weber MD and Raymond A. Pensy MD

    78 Clavicle Fractures, 469
    Chad Myeroff MD and Michael D.McKee MD FRCS(C)

    79 Acromioclavicular Joint, 475
    Chad Myeroff MD and Michael D. McKee MD FRCS (C)

    80 Proximal Humeral Fractures, 481
    Benjamin Kopp MD and David Ring MD PhD

    81 Humeral Shaft Fractures, 487
    David J. Hak MD MBA FACS and Cyril Mauffrey MD FRCS FACS

    82 Distal Humerus Fractures, 491
    Brandon Girardi MD, Emil H. Schemitsch MD, and Aaron Nauth MD MSc

    83 Elbow Dislocations, 499
    Lisa C. Howard MD and Jason W. Pollock MD

    84 Radial Head Fractures, 505
    James D. Spearman Jr MD MBA, David Ring MD PhD, and Lee M. Reichel MD

    85 Olecranon Fractures, 509
    Michael C. Daly MD and Jesse B. Jupiter MD

    86 Forearm Fractures, 515
    Habeeb Khan CCPA and Rudolf W. Poolman MD PhD

    87 Distal Radius Fractures, 521
    Boris A. Zelle MD and Riikkaa E. Nomides MD

    88 Carpal Dislocations, 525
    Carl Nunziato MD, Geert A. Buijze MD PhD, and David Ring MD PhD

    89 Carpal Fractures, 529
    Bert Perey MD FRCSC, Emanuelle Villemaire-Côté MD FRCSC, and Francesc A. Marcano-Fernández MD PhD

    90 Metacarpal Fractures, 537
    Christina Ward MD

    IV.III Pelvis and Lower Extremity

    91 Pelvic Fractures, 541
    G. Yves Laflamme MD FRCS(c), Jonah Hébert-Davies MD FRCS(c)c, and Dominique M.Rouleau MD MSc FRCS(c)

    92 Acetabular Fractures, 547
    Juan Antonio Porcel Vázquez MD and Ernesto Guerra-Farfán

    93 Hip Dislocations, 553
    Luis Felipe López MD, Carlos Prada MD MHSc, Brett D. Crist MD FACS, and Gregory J. Della Rocca MD PhD FACS

    94 Femoral Head Fractures, 559
    Kevin D. Phelps MD, Joshua L. Gary MD, and Milton Lee "Chip" Routt Jr MD

    95 Femoral Neck Fractures in Younger Patients, 565
    Malynda Wynn MD, Trevor Gulbrandsen MD, Michael Willey MD, and Matthew Hogue MD

    96 Femoral Neck Fractures in the Elderly, 571
    Dylan McCreary BA, Brian P. Cunningham MD, and Marc Swiontkowski MD

    97 Extracapsular Hip Fractures, 577
    Luke A. Lopas MD, Andrew F. Tyler MD PhD, and Samir Mehta MD

    98 Subtrochanteric Femur Fractures, 583
    John Morellato BSc (Pharm) MBBS (Hons) FRCSC, Steven Papp BSc MSc MD FRCSC, Wade Gofton BSc MSc MD FRCSC, and Allan Liew BSc MD FRCSC

    99 Femoral Shaft Fractures, 589
    Costas Papakostidis MD and Peter V. Giannoudis MD FACS FRCS

    100 Distal Femur Fractures, 595
    Graeme Hoit MD, Amir Khoshbin MD, and Rudolf W. Poolman MD PhD

    101 Proximal Tibia Fractures, 601
    Daniel Axelrod MD, Richard Jenkinson MD MSc FRCSC, and Hans Kreder MD MPH FRCSC

    102 Tibial Shaft Fractures, 607
    Taylor Yong MD MS, Ilda Molloy MD MS, and Leah Gitajn MD

    103 Intra-Articular Distal Tibia (Pilon/Plafond) Fractures, 613
    Luc Rubinger MD, Seper Ekhtiari MD MSc, and Peter J. O'Brien MD

    104 Malleolar Fractures, 619
    Daniel Axelrod MD and David W. Sanders MD FRCSC

    105 Talus Fractures, 625
    Pablo Mery MD and Carlos Prada MD MHSc

    106 Calcaneal Fractures, 631
    Richard E. Buckley MD FRCSC

    107 Lisfranc Injuries, 637
    Robin R. Elliot MA FRCS, Nicholas B. Jorgensen MBBS, and Terrence S. Saxby MBBS FRACS

    108 Fifth Metatarsal Fractures, 643
    Robin R. Elliot MA FRCS, Nicholas B. Jorgensen MBBS, and Terrence S. Saxby MBBS FRACS

    Section V Spine

    109 Mechanical Neck Pain, 651
    Kenneth Nwosu MD and Thomas Cha MD MBA

    110 Whiplash, 655
    Eren O. Kuris MD and Alan H. Daniels MD

    111 Cervical Radiculopathy and Myelopathy, 659
    Michael Fehlings MD PhD FACS FRCSC and Jetan Badhiwala MD

    112 Mechanical Low Back Pain: Operative Management, 665
    Pranay Patel MD, Ian Buchanan MD, Zorica Buser PhD, and Jeffrey C. Wang MD

    113 Mechanical Low Back Pain: Nonoperative Management, 671
    Kirkham Wood MD and Craig McMains MD

    114 Neurogenic Claudication, 677
    Gregor Lønne MD PhD and Øystein Nygaard MD

    115 Lumbar Radiculopathy, 683
    Daniel G. Tobert MD and James D. Kang MD

    116 Adolescent and Adult Spinal Deformity: Nonoperative Management, 687
    Patrick Thornley MD and Colby Oitment MD FRCSC

    117 Adolescent and Adult Spinal Deformity: Operative Management, 693
    Peter G. Passias MD, Frank A. Segreto MD, Samantha R. Horn BA, and Cole A. Bortz BA

    118 Metastatic/Myeloma Disease, 699
    Marco Ferrone MD and Justin Bulcher MSc

    119 Spinal Infections, 705
    Stuart D. Kinsella MD MTR, Lauren B. Barton BS, and Andrew J. Schoenfeld MD MSc

    Section VI Sports Medicine

    VI.I General

    120 Ergogenic Aids, 713
    Michael J. O'Brien MD

    VI.II Shoulder

    121 First Time Shoulder Dislocation, 717
    Dane Swinehart MD, Jordan Meiss MD, and Charles Cox MD

    122 Recurrent Shoulder Instability, 723
    Joost I. P. Willems MD, Amber von Gerhardt MD, W. Jaap Willems MD, and Arthur van Noort MD PhD

    123 Rotator Cuff Tears, 729
    Alberto Blanco MD, Montserrat García-Portabella MD, Lledó Batalla MD, and Josep Massons MD

    124 Massive and Irreparable Rotator Cuff Tears, 735
    Brandon J. Erickson MD and Joshua S. Dines MD

    125 Subacromial Pain Syndrome, 739
    Egbert J. D. Veen MD and Ron L. Diercks MD

    126 Pathology of the Long Head of the Biceps, 743
    Daniel Wang BA, David Ring MD PhD, and Matt Driscoll MD

    127 Superior Labral Tears and Throwing Shoulder Injuries, 749
    Michael T. Freehill MD, Jacob M. Kirsch MD, Hiroyuki Sugaya MD, and Jon J. P. Warner MD

    VI.III Elbow

    128 Ulnar Collateral Ligament Injuries of the Elbow, 755
    Frank G. J. Loeffen MD, Izaäk F. Kodde MD PhD, and Denise Eygendaal MD PhD

    129 Lateral Epicondylitis (Tennis Elbow), 761
    Neeru Jayanthi MD

    130 Osteochondritis Dissecans Lesions of the Elbow, 769
    Matthew Smith MD and Mitchel Obey MD

    VI.IV Hip

    131 Labral Tears, 775
    Chetan Gohal MD, Nolan S. Horner MD, and Marc R. Safran MD

    132 Femoroacetabular Impingement, 779
    Marc J. Philippon MD, Ioanna K. Bolia MD, and Karen K. Briggs MPH

    VI.V Knee

    133 Initial Management of the Sports Injured Knee, 783
    Marc Aguilar Garcia MD, Carla Carbonell Rosell MD, and Joan Pijoan Bueno MD

    134 Meniscal Tears, 787
    Nicola Maffulli MD MS PhD FRCS (Orth), Domiziano Tarantino MD, and Rocco Aicale MD

    135 Anterior Cruciate Ligament Injuries, 793
    Aaron Gazendam MD, Darren de SA MD, and Freddie Fu MD

    136 Posterior Cruciate Ligament Injuries, 799
    Chetan Gohal MD, Nolan S. Horner MD, Jihad Abouali MD, and John Theodoropoulos MD MSc

    137 Combined Anterior Cruciate Ligament and Medial Collateral Ligament Injuries, 805
    Domiziano Tarantino MD, Rocco Aicale MD, and NicolaMaffulli MD MS PhD FRCS (Orth)

    138 Multiligamentous Knee Injuries, 811
    James P. Stannard MD and Hee Young Lee MD

    139 Posterolateral Corner Injuries, 815
    Nolan S. Horner MD, Chetan Gohal MD, Olufemi R. Ayeni MD PhD, and Daniel B. Whelan MD MSc

    140 Lateral Extra-Articular Tenodesis Procedures and the Anterolateral Ligament, 819
    Felipe Moreira MD, Merce Reverté MD PhD, Enric Castellet MD, and Joan Minguell MD PhD

    141 Cartilage Lesions of the Knee, 825
    Mario Hevesi MD, Aaron J. Krych MD, and Daniël B. F. Saris MD PhD

    142 Patellofemoral Pain Syndrome (Runner's Knee), 831
    Carlos Prada MD MHSc and Sebastián Irarrázaval MD

    143 Osteotomy and Lower Extremity Realignment Procedures, 837
    Jayson Lian BA, Darren de SA MD, João V. Novaretti MD, and Volker Musahl MD

    VI.VI Foot & Ankle

    144 Ankle Ligament Injuries, 843
    Gwendolyn Vuurberg PhD, J. Nienke Altink BSc, Rover Krips MD PhD, and Gino M. M. J. Kerkhoffs MD PhD

    145 Achilles Tendinopathy, 849
    Domiziano Tarantino MD, Rocco Aicale MD, and Nicola Maffulli MD MS PhD FRCS (Orth)

    Section VII Wrist

    146 Distal Radius Malunions, 855
    Muhanned Ali MD, Roberto S. Rosales MD PhD, and Isam Atroshi MD PhD

    147 Distal Radial-Ulnar Joint, 861
    Nina Suh MD

    148 Wrist Osteoarthritis, 867
    Randy Bindra MD

    149 Rheumatoid Wrist Reconstruction, 873
    Warren Hammert DDS MD

    150 Acute Scaphoid Fractures, 877
    Joseph J. Dias MD (Research) FRCS MBBS

    151 Scaphoid Nonunions, 883
    Anne Eva J. Bulstra MD, Job N. Doornberg MD PhD, Myriam C. Obdeijn MD PhD, and Geert A. Buijze MD PhD

    152 Carpal Instability, 889
    Jessica B. Hawken MD and Aviram M. Giladi MD MS

    153 Kienböck's Disease, 895
    Simon B. M. MacLean and Gregory I. Bain

    154 Trapeziometacarpal Osteoarthritis, 899
    Jeremiah D. Johnson MD, Jennifer M. Brewer BA, and Jennifer Moriatis Wolf MD

    Section VIII Hand

    155 Carpal Tunnel Syndrome: Nonoperative Management, 907
    Thomas A. Miller MD FRCPC, Christopher Doherty MD MPH FRCSC, and Douglas C. Ross MD MEd FRCSC

    156 Carpal Tunnel Syndrome: Operative Management, 913
    Douglas C. Ross MD MEd FRCSC, Christopher Doherty MD MPH FRCSC, and Thomas A. Miller MD FRCPC

    157 Carpal Tunnel Release: Minor Procedure Room or Operating Room?, 917
    Kevin Cheung MD and Hannah St Denis-Katz MD

    158 Thumb Carpometacarpal Osteoarthritis, 921
    Ryan Wolek MD, Steven McCabe MD MSc, and Matthew Furey MD MSc

    159 Flexor Tendon Injuries: Surgical Management, 925
    Robert M. Szabo MD MPH and Shima Sokol MD

    160 Flexor Tendon Injuries: Rehabilitation, 931
    Matthew McRae MD, Mark McRae MD, Daniel Waltho MD, and Jenny Santos MSc

    161 Extensor Tendon Injuries, 935
    Noor Alolabi MD, Monica Alderson MSc, and Carolyn M. Levis MD MSc

    162 Dupuytren's Disease, 947
    Lauren Willoughby BMSc MD FRCSC, Daniel Waltho MD, Marta Karpinski BHSc, and Achilleas Thoma MD MSc

    163 Rheumatoid Hand Reconstruction, 953
    Kevin C. Chung MD MS, Oluseyi Aliu MD, and Sandra V. Kotsis MPH

    164 Replantation, 957
    Serge Goekjian MD FRCS (C), Lucas Gallo BHSc MD (c), and Achilleas Thoma MD MSc

    165 Ulnar Neuropathy, 963
    Christopher DohertyMDMPH FRCSC, Thomas A. Miller MD FRCPC, and Douglas C. Ross MD MEd FRCSC

    166 Finger Fractures, 969
    Claire Ryan MD and David Ring MD PhD

    Section IX Oncology

    167 Radiation Therapy in Soft Tissue Sarcoma, 975
    Anthony Bozzo MD MSc, Aaron Gazendam MD, and Kurt R. Weiss MD

    168 Chemotherapy in Soft Tissue Sarcoma, 981
    Robert J. Wilson II MD, Jennifer L. Halpern MD, Jill Gilbert MD, Ginger E. Holt MD, Vicki L. Keedy MD, and Herbert S. Schwartz MD

    169 Surgical Margins in Soft Tissue Sarcoma, 993
    Eugenia Schwarzkopf MD, Tomohiro Fujiwara MD, and John H. Healey MD

    170 Allograft versus Megaprosthesis, 999
    Kelly C. Homlar MD, Robert J. Wilson II MD, Jessica Rose Wilson MD MSCI, Jennifer L. Halpern MD, Herbert S. Schwartz MD, and Ginger E. Holt MD

    171 Biopsy of Soft Tissue Masses, 1005
    Aaron Gazendam MD, Anthony Bozzo MD MSc, Casey Wang MD, and David Wilson MD MASc

    172 Denosumab in Giant Cell Tumors of Bone, 1011
    Michael Parry MD and Robert Grimer MD

    Section X Pediatrics

    173 Outcomes in Pediatric Orthopedics, 1019
    Unni G. Narayanan MBBS MSc FRCS(C)

    174 Cerebral Palsy, 1029
    Vedant Kulkarni MD

    175 Pediatric Osteoarticular Infections, 1035
    Brice Ilharreborde MD, Cindy Mallet MD, and Dimitri Ceroni MD

    176 Simple Bone Cysts, 1041
    Cristina Alves MD FEBOT, Inês Balacó MD, Marta Salom Taverner MD PhD, Thomas Wirth MD PhD, and Michiel Van De Sande MD PhD

    177 Pediatric Clavicle Fractures, 1047
    Benton E. Heyworth MD and Nirav Pandya MD

    178 Supracondylar Humerus Fractures, 1053
    Ravi Brar MD MPH, David Skaggs MD MMM, and Sanjeev Sabharwal MD MPH

    179 Adolescent Spondylolisthesis, 1061
    Matthew E. Oetgen MD MBA and M. Timothy Hresko MD

    180 Early Onset Scoliosis, 1067
    Jason Pui Yin Cheung MBBS MMedSc MS FHKAM (orth) FRCS(orth) FHKCOS(Edin), Susan Nelson MD MPH, James O. Sanders MD, and Ron El-Hawary MD MSc FRCS (C)

    181 Developmental Dysplasia of the Hip, 1075
    Emily K. Schaeffer PhD and Wudbhav N. Sankar MD

    182 Legg-Calvé-Perthes Disease, 1081
    Benjamin Joseph MS Orth MCh Orth FRCS Ed and Hitesh Shah MS Orth

    183 Slipped Capital Femoral Epiphysis, 1087
    Eduardo Novais MD and Randy Loder MD

    184 Pediatric Femoral Shaft Fractures, 1093
    Matthew Winterton MD, Shital Parikh MD FACS, and Keith Baldwin MD MSPT MPH

    185 Infantile Blount Disease, 1099
    Steven M. Rivero MD and Sanjeev Sabharwal MD MPH

    186 Pediatric Anterior Cruciate Ligament Injuries, 1107
    Lindsay Schlichte MS, Colleen Wixted BS, and Daniel Green MD MS FACS

    187 Clubfoot, 1113
    Anna D. Vergun MD and Peter Moskal MD

    188 Tarsal Coalitions, 1119
    Joseph Fox MD and Maryse Bouchard MD MSc

    Index, 1125