Description
Springer Experimental Design And Reproducibility In Preclinical Animal Studies 2021 Edition by Morgado J.M.S.
This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches on factors that may impact the reproducibility of animal studies including: the animal genetic background, the animal microbial flora, environmental and physiological variables affecting the animal, animal welfare, statistics and experimental design, systematic reviews of animal studies, and the publishing process. _x000D__x000D_The book addresses advanced undergraduates, graduate students and all scientists working with animals._x000D_ Table of contents :- 1. An introduction to reproducibility in the context of animal research 2. Rodent Genetics 2.1. Introduction to Mendelian genetics and genomics2.2. Standardized strains of laboratory rodents2.3. Genetically altered (GA) rodents 2.4. Genetic quality control for mice and rats2.5. Mouse and rat phenomics3. Animal and environmental factors that influence reproducibility 4. Microbiology and Microbiome 5. Effects of untreated pain, anesthesia and analgesia in animal experimentation 6. Why do we need a statistical experiment design? 7. Statistical tests and Sample size calculations 8. Design of experiments 9. Scholarly Publishing and Scientific Reproducibility 10. Systematic reviews 11. Planning animal experiments