Description
Wiley Hoffbrand's Essential Haematology 2020 Edition by A. Victor Hoffbrand , David P. Steensma
The new and fully updated edition of the definitive haematology textbook for undergraduate and postgraduate students and traineesHoffbrand's Essential Haematology is widely regarded as the most authoritative introduction to the subject available, helping medical students and trainee doctors understand the essential principles of modern clinical and laboratory haematology for nearly four decades. Now in its eighth edition, this market-leading textbook introduces the formation and function of blood cells and the diseases that arise from dysfunction and disruption of these processes.Beautifully presented with over 300 stunning colour illustrations, the new edition has been thoroughly updated to reflect recent advances in knowledge of the pathogenesis of blood diseases and their diagnosis and treatment. This new text:Describes disorders and diseases of the blood such as the various anaemias and white cell disorders, leukaemias, lymphomas and myeloma, as well as bleeding and thrombotic disordersIncorporates the latest World Health Organization (WHO) classification of haematological neoplastic diseasesReviews contemporary application of multiparameter flow cytometry, DNA sequencing and other technologies in evaluating patients with suspected haematological diseaseDiscusses the therapeutic use of chimeric antigen T-cells, mono- and bi-specific monoclonal antibodies, inhibitors of intracellular signalling pathways and direct orally acting anticoagulantsIncludes sections on blood transfusion and the haematological aspects of systemic diseases, pregnancy and the neonateHoffbrand's Essential Haematology is a vital resource for all students and trainees, and a valuable reference for practicing specialists wishing to update their knowledge. Table of Contents : Preface to the Eighth Edition viPreface to the First Edition viiHow to use your textbook viiiAbout the companion website x1 Haemopoiesis 12 Erythropoiesis and general aspects of anaemia 113 Hypochromic anaemias 274 Iron overload 425 Megaloblastic anaemias and other macrocytic anaemias 506 Haemolytic anaemias 647 Genetic disorders of haemoglobin 788 The white cells, part 1: granulocytes, monocytes and their benign disorders 969 The white cells, part 2: lymphocytes and their benign disorders 11110 The spleen 12611 The aetiology and genetics of haematological neoplasia 13212 Management of haematological malignancy 14713 Acute myeloid leukaemia 15814 Chronic myeloid leukaemia 17215 Myeloproliferative neoplasms 18216 Myelodysplastic syndromes 19617 Acute lymphoblastic leukaemia 20618 The chronic lymphocytic leukaemias 21919 Hodgkin lymphoma 22920 Non-Hodgkin lymphomas 23821 Multiple myeloma and related plasma cell neoplasms 25522 Aplastic anaemia and bone marrow failure 27223 Haemopoietic stem cell transplantation 28124 Platelets, blood coagulation and haemostasis 29625 Bleeding disorders caused by vascular and platelet abnormalities 31226 Coagulation disorders 32427 Thrombosis 1: pathogenesis and diagnosis 33828 Thrombosis 2: treatment 34729 Haematological changes in systemic diseases 36030 Blood transfusion 37231 Pregnancy and neonatal haematology 386Appendix 395Index 401