Description
Ip Innovative Publication Pvt Ltd Immunological Techniques Interpretations Validation and Safety Measures by Ankita Joshi and Prof R S Chauhan
Immunity is the resistance of the body expressed through various cellular, physiological and biochemical reactions in the body. Whenever any foreign material/ infection enters in the body, the immune system activates and initiates production of immunity against those particular foreign material (infection/antigen). Mainly the immunity developed in the body is either in the form of humoral or cell mediated immune response and is specific to a particular antigen against which it is developed in the body. In the process of disease diagnosis, it is important to either detect the presence of antigen in the body or antibodies or specific T cells for the confirmation of the disease. For this purpose, various immunological techniques are employed to confirm the tentative diagnosis of physician/clinician. In the present book, various immunological techniques are described, including agglutination, precipitation, CFT, ELISA, DIA and other related techniques. These techniques are described in a very simple language and written by very experienced persons including the tit-bits of each tests so that the readers can understand easily and may employ these techniques in their research. Besides, validation 01 the techniques is described along with a diagnostic, sensitivity and specificity to determine the assay performance and reliability. Measurement of uncertainty related with each diagnostic test has also been discussed in this book. The safety measurement adopted in diagnostic laboratory along with the first aid in case of accidents are being well described. Each technique is well illustrated through diagram or photographs so that the basic principle of the technique is clearly understood. Authors arc having very rich experience of working in a diagnostic laboratory not only as technical expert or as a diagnostician, but also they are having the experience of research managers and management of immunological laboratory and diagnostic laboratory.