Description
John Wiley And Sons Mass Spectrometry In Biophysics: Conformation And Dynamics Of Biomolecules by Kaltashov
This title presents the first systematic summary of biophysical mass spectrometry techniques. Recent advances in mass spectrometry (MS) have pushed the frontiers of analytical chemistry into the biophysical laboratory. As a result, the biophysical community's acceptance of MS-based methods, used to study protein higher-order structure and dynamics, has accelerated the expansion of biophysical MS. Despite this growing trend, until now no single text has presented the full array of MS-based experimental techniques and strategies for biophysics. "Mass Spectrometry in Biophysics" expertly closes this gap in the literature. Covering the theoretical background and technical aspects of each method, this much-needed reference offers an unparalleled overview of the current state of biophysical MS."Mass Spectrometry in Biophysics" begins with a helpful discussion of general biophysical concepts and MS-related techniques.
In this title, subsequent chapters address: modern spectrometric hardware; high-order structure and dynamics as probed by various MS-based methods; techniques used to study structure and behavior of non-native protein states that become populated under denaturing conditions; kinetic aspects of protein folding and enzyme catalysis MS-based methods used to e.