Description
Elsevier Medical Pharmacology and Therapeutics by Derek G. Waller, Anthony Sampson
Medical Pharmacology & Therapeutics provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA.This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class. Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines.A clinical focus throughout - suitable for medical, nursing and other healthcare students throughout their trainingThorough update of clinically-relevant medicines to ensure best practiceInformation aligned with the British National Formulary (BNF), NICE guidelines and relevant professional benchmarks Comprehensive drug compendia allow all drugs to be identified and placed within their respective classesExtensive self-assessment questions to support learning and revisionNew to this edition Expanded discussion of the pathophysiology and management of shock Revised discussion of the management of chronic painConsideration of treatment of Covid-19Expanded discussion of the pathophysiology and management of shock Revised discussion of the management of chronic painConsideration of treatment of Covid-19 Table of Contents : PrefaceDrug Dosage and NomenclatureSECTION 1 GENERAL PRINCIPLES 1. Principles of Pharmacology and Mechanisms of Drug Action 2. Pharmacokinetics 3. Drug Discovery, Safety and Efficacy 4. Neurotransmission and the Peripheral Autonomic Nervous System SECTION 2 THE CARDIOVASCULAR SYSTEM5. Ischaemic Heart Disease6. Systemic and Pulmonary Hypertension 7. Heart Failure and Shock8. Cardiac Arrhythmias9. Cerebrovascular Disease and Dementia 10. Peripheral Artery Disease11. HaemostasisSECTION 3 THE RESPIRATORY SYSTEM 12. Asthma and Chronic Obstructive Pulmonary Disease 13. Respiratory Disorders: Cough, Respiratory Stimulants, Cystic Fibrosis, Idiopathic Pulmonary Fibrosis and Neonatal Respiratory Distress Syndrome SECTION 4 THE RENAL SYSTEM14. Diuretics15. Disorders of Micturition 16. Erectile DysfunctionSECTION 5 THE NERVOUS SYSTEM 17. General Anaesthetics18. Local Anaesthetics19. Opioid Analgesics and the Management of Pain 20. Anxiety, Obsessive-Compulsive Disorder and Insomnia 21. Schizophrenia and Bipolar Disorder22. Depression, Attention Deficit Hyperactivity Disorder and Narcolepsy 23. Seizures and Epilepsy24. Extrapyramidal Movement Disorders and Spasticity 25. Other Neurological Disorders: Multiple Sclerosis, Motor Neuron Disease and Guillain-BarreSyndrome26. Migraine and Other HeadachesSECTION 6 THE MUSCULOSKELETAL SYSTEM 27. The Neuromuscular Junction and Neuromuscular Blockade 28. Myasthenia Gravis29. Nonsteroidal Anti-inflammatory Drugs30. Rheumatoid Arthritis, Other Inflammatory Arthritides and Osteoarthritis31. Hyperuricaemia, Gout and Pseudogout SECTION 7 THE GASTROINTESTINAL SYSTEM 32. Nausea and Vomiting33. Dyspepsia, Peptic Ulcer Disease and Gastrooesophageal Reflux Disease 34. Inflammatory Bowel Disease35. Constipation, Diarrhoea and Irritable Bowel Syndrome 36. Liver Disease37. ObesitySECTION 8 THE IMMUNE SYSTEM 38. The Immune Response and Immunosuppressant Drugs 39. Antihistamines and Allergic DiseaseSECTION 9 THE ENDOCRINE SYSTEM AND METABOLISM 40. Diabetes Mellitus41. The Thyroid and Control of Metabolic Rate 42. Calcium Metabolism and Metabolic Bone Disease 43. Pituitary and Hypothalamic Hormones44. Corticosteroids (Glucocorticoids and Mineralocorticoids) 45. Female Reproduction46. Androgens, Antiandrogens and Anabolic Steroids 47. Anaemia and Haematopoietic Colony-Stimulating Factors 48. Lipid DisordersSECTION 10 THE SKIN AND EYES 49. Skin Disorders 50. The EyeSECTION 11 CHEMOTHERAPY 51. Drugs for Infections52. Drugs for CancerSECTION 12 GENERAL FEATURES, TOXICITY AND PRESCRIBING 53. Drug Toxicity and Overdose54. Substance Abuse and Dependence 55. Prescribing, Adherence and Information About Medicines 56. Drug Therapy in Special Situations \Index