NMR Spectroscopy in Pharmaceutical Analysis (Hard Back) at Meripustak

NMR Spectroscopy in Pharmaceutical Analysis (Hard Back)

Books from same Author: Holzgrabe

Books from same Publisher: Elsevier Science

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  • General Information  
    Author(s)Holzgrabe
    PublisherElsevier Science
    ISBN9780444531735
    Pages528
    LanguageEnglish
    Publish YearJanuary 2008

    Description

    Elsevier Science NMR Spectroscopy in Pharmaceutical Analysis (Hard Back) by Holzgrabe

    For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples.


    Key Features:-

    • combines theory, techniques, and concrete applications-all of which closely resemble the laboratory
    • considers international pharmacopoeias, addressing the concern for licensing
    • features the work of academics and researchers, appealing to a broad readership