Description
Oxford Neuroprogression in Psychiatry 2019 Edition by Flavio Kapczinski, Michael Berk, Pedro Vieira da Silva Magalhaes
Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders,such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found inpatients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression.Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder. Table of Contents :- 1: Luis Guilherme Streb, Michael Berk, and Flavio Kapczinski: A short introductory note on neuroprogression and staging in psychiatry2: Iria Grande, Flavio Kapczinski, Sebastian Caminoa, Gustavo Vazquez, and Eduard Vieta: Allostasis and neuroprogression in major psychiatric disorders3: Elisa Brietzke, Ana S. Yamagata, Pawan K. Maurya, and Lucas B. Rizzo: Neuroprogression and accelerated aging in severe psychiatric disorders4: Ana C. Andreazza, Rajas P. Kale, Angela Duong, Fabio Molina, and Susannah J.Tye: Mitochondrial function and inflammation pathways in the neuroprogression of mental disorders5: Elisa Brietzke, Ana S. Yamagata, Raphael Cerqueira, Lucas B. Rizzo, Roger S. McIntyre, and Rodrigo B. Mansur: The role of immuno-inflammatory abnormalities in neuroprogression6: George Anderson and Michael Maes: Depression and neuroprogression: Sirtuins and mitochondria as crucial hubs7: Ryan M. Cassidy, Ives Cavalcante Passos, and Marcia Kauer-Sant'Anna: Neuroprogression in post-traumatic stress disorder8: Giampaolo Perna, Elisa Mingotto, Alessandra Alciati, and Daniela Caldirola: Neuroprogression in anxiety disorders9: Adriane R. Rosa and Flavia Lima: Functioning and illness progression in severe mental illness10: Emre Bora: Neuropsychological functioning and neuroimaging in bipolar disorder: Evidence of neuroprogression11: Francisco Romo-Nava, Jenni Farrow, Luis Rodrigo Patino, Fabiano Nery, Caleb M. Adler, and Melissa P. DelBello: Neuroprogression in children and adolescents with bipolar disorder12: Anne Orgler Sordi, Silvia Bassani Schuch-Goi, and Lisia von Diemen: Substance abuse and neuroprogression13: Adrian L. Lopresti and Peter D. Drummond: Lifestyle and neuroprogression: Diet, sleep, and exercise14: Jonathan M. Gregory, Benjamin I. Goldstein, and Roger S. McIntyre: The pernicious procession of somatoprogression