Description
HUMANA PRESS Neuroprotection Methods And Protocols 1 Ill Edition 2007 Edition by TIZIANA BORSELLO
This book examines current research into the role of neuronal death in cell signaling pathways, and its role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. After introducing neurodegenerative, traumatic, and ishemic disorders, the authors cover in vitro and animal systems, and cellular and molecular mechanisms. TABLE OF CONTENTS1) Neuronal death and neuroprotection (REVIEW CHAPTER)Mariaelena Repici, Jean Mariani and Tiziana Borsello2) The use of propidium iodide to assess excitotoxic neuronal death inprimary mixed cortical cultures.Anthony C Lau, Hong Cui, Michael Tymianski3) A modified silver technique (De Olmos Stain) for assessment ofneuronal and axonal degeneration.Tatyana I. Tenkova and Mark P. Goldberg4) Model of acute injury to study neuroprotection.Michal Schwartz and Jonathan Kipnis5) Organotypic entorhino-hippocampal slice cultures - a tool to studythe molecular and cellular regulation of axonal regeneration andcollateral sprouting in vitro.Domenico Del Turco and Thomas Deller6) Role of Nrf2-dependent ARE-driven antioxidant pathway inneuroprotection.Jiang Li, Marcus J. Calkins, Delinda A. Johnson, Jeffrey A. Johnson7) Biochemical methods to assess the coupling of brain energymetabolism in control and disease states.Jennifer Zechel, David W. Lust, Michele Puchowicz8) A Method for Isolating Prosurvival Targets of NF-=B/RelTranscription Factors.Francesca Zazzeroni, Christian Kuntzen, Can G. Pham, Salvatore Papa,Concetta Bubici, James R. Knabb, and Guido Franzoso9) Functional cloning of genes regulating apoptosis in neuronal cells.Roberta Visconti and Luciano D'Adamio10) Characterization of mRNA Expression in Single Neurons.David M. Lin, Brandon Loveall, John Ewer, David L. Deitcher, andNikolaus J. Sucher11) Brain on a chip: a method to detect novel neuroprotective candidatetargets.Yang Tang and Myriam Bernaudin12) Intracerebral infusion of neurotrophic factors.Theo Hagg13) Synthesis of Cell Penetrating Peptides and Their Application inNeurobiology.Gunnar P.H. Dietz and Mathias Bahr14) The stem cells as a potential treatment for neurodegeneration.DanielaFerrari, Angelo Luigi Vescovi, Daniele Bottai15) In Vivo Tomographic Neuroimaging Studies of Neurodegeneration andNeuroprotection (REVIEW CHAPTER)Rikki N. Waterhouse and Jun Zhao