Description
Taylor and Francis Ltd Organ Specific Drug Delivery and Targeting to the Lungs 1st Edition 2022 Hardbound by Narang, Ajit S.
Organ Specific Drug Delivery and Targeting to the Lungs provides up to date information on the multidisciplinary field of particle engineering and drug delivery to the lungs, including advancements of nanotechnology. The text presents a unique, pragmatic focus with case studies, that help translate scientific understanding to practical implementation. In addition to highlighting the successful case studies, it also offers practical advice on watchouts, limitations, and 'bookend' boundaries involved in the stages of testing and development.Additional Features Include:Provides an account of particle engineering, discovery, biology, development, and delivery in relation with the advancements of nanotechnology, unlike any previous book. Brings together the leading experts and researchers in the field to critically assess and discuss various topics influencing drug delivery. Highlights the interplay of different scientific disciplines and the balance of requirements that are critical to molecule and product design.With the strategic focus on what matters during new product development, this book provides a guide to understanding and navigating new drug discovery and development for lung targets. Chapter 01Estimating Clinically Relevant Measures of Inhaled Pharmaceutical Aerosol Performance with Advanced In Vitro and In Silico MethodsChapter 02In Vitro Assessment of Drug Release, Dissolution, and Absorption in the LungChapter 03Lung-on-a-Chip and Lung Organoid ModelsChapter 04Interaction between Inhalable Nanomedicines and Pulmonary SurfactantChapter 05Particle engineering for pulmonary drug deliveryChapter 06Particle Architectonics for Pulmonary Drug DeliveryChapter 07Engineered Particles for Aerosolisation and Lung DepositionChapter 08Recent advances in inhalable nanomedicine for lung cancer therapyChapter 09Thin-Film Freeze-Drying Process for Versatile Particles for Inhalation Drug DeliveryChapter 10Nanoparticles as specific drug carriersChapter 11Surface modification of micronized drug particles for aerosolizationChapter 12Spray Dried Particles for InhalationChapter 13Inhalation Aerosol Phospholipid Particles for Targeted Lung DeliveryChapter 14NebulizersChapter 15Protein and Peptide Delivery to the Lung via Inhalation Chapter 16Exosomes Based Drug Delivery for Lung Cancer Treatment