Pathogenesis And Treatment In IGA Nephropathy An International Comparison at Meripustak

Pathogenesis And Treatment In IGA Nephropathy An International Comparison

Books from same Author: TOMINO Y

Books from same Publisher: SPRINGER

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  • General Information  
    Author(s)TOMINO Y
    PublisherSPRINGER
    ISBN9784431555872
    Pages342
    BindingHardbound
    LanguageEnglish
    Publish YearMarch 2016

    Description

    SPRINGER Pathogenesis And Treatment In IGA Nephropathy An International Comparison by TOMINO Y

    This book discusses the latest findings on the pathogenesis and treatment of IgA nephropathy. It particularly focuses on recently recognized initiation and progression factors and the varying treatment strategies in different regions, such as Asia, Europe, and the United States. More than 40 years have passed since Dr. Jean Berger first described primary IgA nephropathy ("Nephropathy with mesangial IgA-IgG deposits") as a new disease entity. Immunohistopathologically, IgA nephropathy is characterized by the granular deposition of IgA (IgA1) and C3 in the glomerular mesangial areas with mesangial cell proliferation and the expansion of mesangial matrices. It is clear that IgA nephropathy is one of the most common types of chronic glomerulonephritis in the world. This disease may lead to end-stage kidney disease, with its enormous economic impact on healthcare everywhere. Efforts by many investigators around the world have gradually clarified various aspects of the pathogenesis and treatment of IgA nephropathy. However, there are many controversial strategies for the treatment of patients with IgA nephropathy throughout the world, as there are several limitations.