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Pharmaceutical Toxicology in Practice A Guide to Non- Clinical Development (HB)

Pharmaceutical Toxicology in Practice A Guide to Non- Clinical Development (HB)
Books from same Author: Lodola
Books from same Publisher: John Wiley

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Description

This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in the development of pharmaceuticals, the book proceeds to detail international regulations (including the impact of the new REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk management. Further, the book covers the methods of genetic toxicology (assays, genomics, in vivo screening) as a complement to “traditional” toxicology in the risk assessment and risk management of pharmaceuticals.

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General Information
Author(s)Lodola
PublisherJohn Wiley
ISBN9780470371374
Pages258
BindingHard Back
LanguageEnglish
Publish YearJanuary 2011
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