Description
OXFORD UNIVERSITY PRESS Primer On Multiple Sclerosis 2011 Edition by Barbara S. Giesser MD
Primer on Multiple Sclerosis was developed to provide a comprehensive overview of the clinical and basic science aspects of MS. It is designed to be of practical use to clinical neurologists, and addresses all of the major issues that may occur in the management of persons with MS. The reader is provided with the latest information on the science of MS, including immunology, genetics, epidemiology and pathology, as well as a summary of the newest directionsin basic science research. Guidelines for diagnosis and appropriate use of diagnostic modalities are presented. All clinical aspects of MS are discussed, including extensive information on aspects that may be more challenging for the neurologist to manage, such as sleep disorders and pain.Disease modifying therapies, including those that are FDA approved, as well as off label and experimental therapies are discussed. Finally, there are chapters on employment and legal issues, as well as an overview of clinical trials and clinical trial outcome measures, which are helpful in reviewing the scientific literature in these areas. ContributorsChapter 1: The History of Multiple Sclerosis: From the Age of Description to the Age of TherapyT. Jock MurrayPart 1: Basic ScienceChapter 2: Genetics and Epidemiology in Multiple SclerosisSreeram V. Ramagopalan and A. Dessa SadovnickChapter 3: Neurophysiology of Multiple SclerosisJefferson C. SlimpChapter 4: Immunology of Multiple SclerosisLaura Piccio and Anne H. CrossChapter 5: Taking a Microscopic Look at Multiple SclerosisClaudia F. LucchinettiPart 2: Diagnosis and PrognosisChapter 6: Diagnosis of Multiple SclerosisLoren A. RolakChapter 7: Neuroimaging in Multiple SclerosisNancy L. SicotteChapter 8: Cerebrospinal Fluid Profile Supporting a Clinical Definite Multiple Sclerosis DiagnosisWallace W. TourtellotteChapter 9: Evoked PotentialsMarc R. NuwerChapter 10: Temporal and Clinical Course of Multiple SclerosisErica Grazioli, Cornelia Mihai, and Bianca Weinstock-GuttmanChapter 11: Outcome Measures in Multiple SclerosisRobert M. HerndonPart 3: Clinical ManifestationsChapter 12: Neuro-Ophthalmologic Manifestations of Multiple SclerosisErik V. Burton and Elliot M. FrohmanChapter 13: Disorders of Mobility in Multiple SclerosisThomas E. McNalley and Jodie K. HaselkornChapter 14: Multiple Sclerosis and PainNorman S. NamerowChapter 15: Management of Urinary and Bowel Dysfunction in Patients with Multiple SclerosisJa-Hong KimChapter 16: Assessment and Treatment of Sexual Dysfunction in Multiple SclerosisFrederick W. FoleyChapter 17: Gender and Reproductive Issues in Multiple SclerosisRhonda VoskuhlChapter 18: Cerebellar and Brainstem Dysfunction in Multiple SclerosisAngeli S. Mayadev and George H. KraftChapter 19: Cognitive Impairment and Mood DisturbancesNicholas G. LaRoccaChapter 20: Fatigue in Multiple SclerosisChristopher Christodoulou, Yashma Patel, and Lauren KruppChapter 21: Sleep Disorders in Multiple SclerosisTiffany Braley and Alon Y. AvidanChapter 22: Pediatric Multiple SclerosisE. Ann Yeh, Tanuja Chitnis, Lauren Krupp, Jayne M. Ness, Dorothee E. Chabas, Nancy Kuntz, and Emmanuelle L. WaubantPart 4: TherapeuticsChapter 23: Immunomodulatory Agents for Relapsing-Remitting Multiple SclerosisLawrence M. SamkoffChapter 24: Immunosuppressive and Novel TherapiesBarbara S. GiesserChapter 25: Complementary and Alternative Medicine in Multiple SclerosisAllen C. BowlingPart 5: Psychosocial IssuesChapter 26: Living with Multiple Sclerosis: The Psychosocial Challenges for Patients and Their Families Rosalind C. KalbChapter 27: Employment and Career Development ConsiderationsPhillip D. Rumrill, Jr. and Steven W. NissenChapter 28: Legal Planning IssuesLaura D. Cooper, Esq.Part 6: ResearchChapter 29: Issues in the Design and Interpretation of Multiple Sclerosis Clinical TrialsStephen Krieger, Svenja Oynhausen, and Aaron MillerChapter 30: Basic Science in Multiple Sclerosis: Progress and PromiseWendy Gilmore and Leslie P. WeinerIndex