Stem Cells And Cancer Stem Cells, Volume 11: Therapeutic Applications In Disease And Injury at Meripustak

Stem Cells And Cancer Stem Cells, Volume 11: Therapeutic Applications In Disease And Injury

Books from same Author: HAYAT

Books from same Publisher: SPRINGER

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  • General Information  
    Author(s)HAYAT
    PublisherSPRINGER
    ISBN9789400773288
    Pages280
    BindingHardbound
    LanguageEnglish
    Publish YearOctober 2013

    Description

    SPRINGER Stem Cells And Cancer Stem Cells, Volume 11: Therapeutic Applications In Disease And Injury by HAYAT

    Volume 11 in this series discusses therapeutic applications of stem cells in disease and tissue injury. Coverage includes pluripotent stem cells, which can give rise to the endodermal, ectodermal, and mesodermal lineages; multipotent stem cells, which can generate all cells in a particular lineage and unipotent stem cells, which can give rise to only one cell type. This volume also examines cancer stem cells, tumor-initiating cells which possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells that comprise the tumor. Coverage extends to molecular mechanisms underlying the derivation and expansion of human embryonic stem cells, the role of specific proteins in the maintenance and inhibition of extraembryonic differentiation of these cells and the role of signaling responsible for the self-renewal of mouse embryonic stem cells. Nine chapters discuss the clinical importance of cancer stem cells, encompassing glioma, leukemia, ovarian cancer, pediatric sarcomas and head and neck squamous cell carcinoma. The role of cancer stem cells is also elucidated in epithelial-to-mesenchymal transition in spreading head and neck squamous cell carcinoma. The book goes on to survey therapeutic application of stem cells of hematopoietic and non-hematopoietic origin for regeneration of bones, including in ost...