Description
ELSEVIER Stroke Pathophysiology Diagnosis And Management 7Ed (Hb 2022) by Grotta J.C.
Authored by the world's foremost stroke experts, this classic text brings you fully up to date with current research findings and management approaches for cerebrovascular disease. Stroke: Pathophysiology, Diagnosis, and Management, 7th Edition, covers every aspect of this fast-moving field, and is an ideal resource for stroke specialists, general neurologists, and other medical professionals with an interest in stroke. You'll find expert clinical guidance, comprehensive pathophysiology coverage, data from recent trials, advances in diagnostic tests, full-color CT images, pathology slides, and much more, for a complete picture of today's stroke medicine._x000D__x000D_Helps you recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan._x000D_Keeps you abreast of the overwhelming volume of studies and guidelines in this dynamic field, providing clear summaries and practical evaluations of all relevant data. _x000D_Contains updates throughout, including the latest clinical trials (thrombectomy, DAWN, DEFUSE), genetics research, prevention research, new therapies, and the new guidelines from the ASA. _x000D_Includes new slides for lectures, covering basic science, case studies, and interventional treatment overviews. _x000D_Features a Key Points summary at the beginning of each chapter so you can quickly find important information. _x000D_Provides abundant full-color CT images and pathology slides that help you make efficient and accurate diagnoses. _x000D_Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices._x000D_ _x000D_
Section 1 Pathophysiology_x000D_
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Introduction_x000D_
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1. Cerebral Vascular Biology in Health and Disease_x000D_
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2. Mechanisms of Thrombosis and Thrombolysis_x000D_
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3. Cerebral Blood Flow and Metabolism: Regulation and Pathophysiology in Cerebrovascular Disease_x000D_
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4. Histopathology of Brain Tissue Response to Stroke and Injury_x000D_
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5. Molecular and Cellular Mechanisms of Ischemia-Induced Neuronal Death_x000D_
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6. Intracellular Signaling: Mediators and Protective Responses_x000D_
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7. The Neurovascular Unit and Responses to Ischemia_x000D_
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8. Mechanisms of Damage After Cerebral Hemorrhage_x000D_
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9. White Matter Pathophysiology_x000D_
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10. Cerebral Ischemia and Inflammation_x000D_
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11. Mechanisms of Plasticity, Remodeling and Recovery_x000D_
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12. Genetics and Vascular Biology of Brain Vascular Malformations _x000D_
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13. Gliovascular Mechanisms and White Matter Injury in Vascular Cognitive Impairment and Dementia_x000D_
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Section 2 Epidemiology and Risk Factors_x000D_
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Introduction_x000D_
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14. Global Burden of Stroke_x000D_
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15. Stroke Disparities_x000D_
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16. Risk Factors and Prevention_x000D_
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17. Prognosis after Stroke_x000D_
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18. Vascular Dementia and Cognitive Impairment_x000D_
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19. Genetic Basis of Stroke Occurrence, Prevention and Outcome_x000D_
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Section 3 Clinical Manifestations_x000D_
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Introduction_x000D_
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20. Classification of Ischemic Stroke_x000D_
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21. Clinical Scales to Assess Patients with Stroke_x000D_
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22. Carotid Artery Disease_x000D_
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23. Anterior Cerebral Artery Disease_x000D_
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24. Middle Cerebral Artery Disease_x000D_
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25. Posterior Cerebral Artery Disease_x000D_
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26. Vertebrobasilar Disease_x000D_
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27. Lacunar Syndromes, Lacunar Infarcts, and Cerebral Small-Vessel Disease_x000D_
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28. Intracerebral Hemorrhage_x000D_
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29. Aneurysmal Subarachnoid Hemorrhage_x000D_
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30. Arteriovenous Malformations and Other Vascular Anomalies_x000D_
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31. Stroke and Other Vascular Syndromes of the Spinal Cord_x000D_
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Section 4 Specific Conditions and Stroke_x000D_
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Introduction_x000D_
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32. Cardiac Diseases_x000D_
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33. Atherosclerotic Disease of the Proximal Aorta_x000D_
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34. Stroke Related to Surgery and Other Procedures_x000D_
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35. Arterial Dissection, Fibromuscular Dysplasia, and Carotid Web_x000D_
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36. Inflammatory and Infectious Vasculopathies_x000D_
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37. Reversible Cerebral Vasoconstriction Syndromes_x000D_
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38. Posterior Reversible Encephalopathy Syndrome_x000D_
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39. Stroke and Substance Abuse_x000D_
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40. Moyamoya Disease_x000D_
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41. Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy_x000D_
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42. Hematologic Disorders and Stroke_x000D_
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43. Migraine and Stroke_x000D_
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44. Cryptogenic Stroke_x000D_
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45. Cerebral Venous Thrombosis_x000D_
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Section 5 Diagnostic Studies_x000D_
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Introduction_x000D_
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46. Ultrasonography_x000D_
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47. Computed Tomography-Based Evaluation of Cerebrovascular Disease_x000D_
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48. Magnetic Resonance Imaging of Cerebrovascular Diseases_x000D_
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49. Cerebral Angiography_x000D_
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50. OMICs in Stroke: Insight into stroke through epigenomics, transcriptomics, proteomics, lipidomics, and metabolomics_x000D_
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Section 6 Therapy_x000D_
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Part A: Medical Therapy_x000D_
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Introduction_x000D_
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51. Stroke Systems of Care and Impact on Acute Stroke Treatment _x000D_
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52. Prehospital and Emergency Department Care of the Patient with Acute Stroke_x000D_
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53. Intravenous Thrombolysis_x000D_
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54. Antithrombotic Therapy for Treatment of Acute Ischemic Stroke_x000D_
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55. General Stroke Management and Stroke Units_x000D_
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56. Critical Care of the Patient with Acute Stroke, _x000D_
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57. Pharmacologic Modification of Acute Cerebral Ischemia_x000D_
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58. Treatment of "Other" Stroke Etiologies_x000D_
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59. Medical Therapy of Intracerebral and Intraventricular Hemorrhage_x000D_
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60. Rehabilitation and Recovery of the Patient with Stroke_x000D_
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61. Interventions to Improve Recovery after Stroke_x000D_
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62. Enhancing Stroke Recovery with Cellular Therapies_x000D_
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63. Antiplatelet Therapy for Secondary Prevention of Stroke_x000D_
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64. Secondary Prevention of Cardioembolic Stroke_x000D_
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65. Design of Stroke-Related Clinical Trials_x000D_
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Part B: Interventional Therapy_x000D_
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Introduction_x000D_
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66. Endovascular Therapy of Extracranial and Intracranial Occlusive Disease_x000D_
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67. Endovascular Treatment of Acute Ischemic Stroke_x000D_
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68. Endovascular Treatment of Intracranial Aneurysms_x000D_
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69. Interventional Therapy of Brain and Spinal Arteriovenous Malformations_x000D_
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70. Dural Arteriovenous Malformations_x000D_
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Part C: Surgical Therapy_x000D_
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Introduction_x000D_
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71. Surgery of Anterior and Posterior Aneurysms_x000D_
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72. Surgery for Intracerebral Hemorrhage_x000D_
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73. Management of Intraventricular Hemorrhage_x000D_
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74. Surgical Management of Cranial and Spinal Arteriovenous Malformations_x000D_
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75. Surgical Management of Cavernous Malformations and Venous Anomalies_x000D_
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76. Indications for Carotid Endarterectomy in Patients with Asymptomatic and Symptomatic Carotid Stenosis_x000D_
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77. Extracranial to Intracranial Bypass for Cerebral Ischemia_x000D_
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78. Decompressive Craniectomy for Infarction and Hemorrhage_x000D_