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Translational Pain Research 2009 Edition at Meripustak

Translational Pain Research 2009 Edition by Lawrence Kruger, Alan R Light , Taylor & Francis Ltd

Books from same Author: Lawrence Kruger, Alan R Light

Books from same Publisher: Taylor & Francis Ltd

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  • General Information  
    Author(s)Lawrence Kruger, Alan R Light
    PublisherTaylor & Francis Ltd
    ISBN9781439812099
    Pages456
    BindingHardback
    LanguageEnglish
    Publish YearNovember 2009

    Description

    Taylor & Francis Ltd Translational Pain Research 2009 Edition by Lawrence Kruger, Alan R Light

    One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes.Distinguished Team of International ContributorsIn addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on:Nociceptor sensitizationMuscle nociceptors and metabolite detectionVisceral afferents in diseaseInnovative rodent model for bone cancer pain Highly specific receptor cloningModular molecular mechanisms relevant to painful neuropathiesThis sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences. Painful Multi-Symptom Disorders: A Systems PerspectiveC. Richard ChapmanNeurotrophic Factors and Nociceptor SensitizationMichael P. Jankowski and H. Richard KoerberThe Role of Visceral Afferents in DiseaseJulie A. Christianson and Brian M. DavisCancer Pain: From the Development of Mouse Models to Human Clinical TrialsJuan Miguel Jimenez Andrade and Patrick MantyhTherapeutic Targeting of Peripheral Cannabinoid Receptors in Inflammatory and Neuropathic Pain StatesIgor SpigelmanMolecular Strategies for Therapeutic Targeting of Primary Sensory Neurons in Chronic Pain SyndromesIchiro Nishimura, Devang Thakor, Audrey Lin, Supanigar Ruangsri, and Igor SpigelmanTransgenic Mouse Models for the Tracing of "Pain" PathwaysAllan I. Basbaum and Joao M. BrazCytokines in PainVeronica I. Shubayev, Kinshi Kato, and Robert R. MyersGlial Modulation in Pain States: Translation into HumansRyan J. Horvath, Edgar Alfonso Romero-Sandoval, and Joyce A. De LeoOn the Role of ATP-Gated P2X Receptors in Acute, Inflammatory, and Neuropathic PainEstelle Toulme, Makoto Tsuda, Baljit S. Khakh, and Kazuhide InoueMyalgia and Fatigue: Translation from Mouse Sensory Neurons to Fibromyalgia and Chronic Fatigue SyndromesAlan R. Light, Charles J. Vierck, and Kathleen C. LightReflex Autonomic Responses Evoked by Group III and IV Muscle AfferentsJennifer L. McCord and Marc P. KaufmanCentral Pain as a Thalamocortical Dysrhythmia: A Thalamic Efference Disconnection?Kerry D. Walton and Rodolfo R. LlinasWhat Can Neuroimaging Tell Us about Central Pain?D.S. Veldhuijzen, F.A. Lenz, S.C. LaGraize, and J.D. GreenspanHuman Brain Imaging Studies of Chronic Pain: Translational OpportunitiesA. Vania ApkarianConsideration of Pharmacokinetic Pharmacodynamic Relationships in the Discovery of New Pain DrugsGarth T. Whiteside and Jeffrey D. KennedyLarge Animal Models for Pain Therapeutic DevelopmentDarrell A. Henze and Mark O. UrbanDrug Discovery and Development for PainSandra R. Chaplan, William A. Eckert III, and Nicholas I. CarruthersIndex