Description
Humana Press Inc. Transplantation Immunology Methods and Protocols by Philip Hornick
Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection._x000D_ Table of contents :- _x000D_
Current Status of Renal Transplantation_x000D_
Christopher J. Callaghan and J. Andrew Bradley_x000D_
_x000D_
Current Status of Liver Transplantation_x000D_
Peter J. Friend and Charles J. Imber_x000D_
_x000D_
Current Status of Clinical Islet Cell Transplantation_x000D_
Jonathan R. T. Lakey, Mohammadreza Mirbolooki, and A. M. James Shapiro_x000D_
_x000D_
Current Status of Lung Transplantation_x000D_
Allan R. Glanville_x000D_
_x000D_
Chronic Rejection in the Heart_x000D_
Philip Hornick and Marlene Rose_x000D_
_x000D_
Direct and Indirect Allorecognition_x000D_
Philip Hornick_x000D_
_x000D_
HLA Typing and Its Influence on Organ Transplantation_x000D_
Stephen Sheldon and Kay Poulton_x000D_
_x000D_
Strategies for Gene Transfer to Solid Organs: Viral Vectors_x000D_
Charlotte Lawson_x000D_
_x000D_
Nonviral Vectors_x000D_
Louise Collins_x000D_
_x000D_
Detection and Clinical Relevance of Antibodies After Transplantation_x000D_
John D. Smith and Marlene Rose_x000D_
_x000D_
Reprogramming the Immune System Using Antibodies_x000D_
Luis Graca and Herman Waldmann_x000D_
_x000D_
In Vitro Assays for Immune Monitoring in Transplantation_x000D_
Maria P. Hernandez-Fuentes and Alan Salama_x000D_
_x000D_
Proteomics and Laser Microdissection_x000D_
Emma McGregor and Ayesha De Souza_x000D_
_x000D_
Real-Time Quantitative Polymerase Chain Reaction in Cardiac Transplant Research_x000D_
Leanne E. Felkin, Anne B. Taegtmeyer, and Paul J. R. Barton_x000D_
_x000D_
Organ Preservation_x000D_
Mark Hicks, Alfred Hing, Ling Gao, Jonathon Ryan, and Peter S. MacDonald_x000D_
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Pharmacological Manipulation of the Rejection Response_x000D_
Peter Mark Anthony Hopkins_x000D_
_x000D_
Experimental Models of Graft Arteriosclerosis_x000D_
Bezhad Soleimani and Victor C. Shi_x000D_
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Index_x000D_