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American Society for Microbiology Virulence Mechanisms of Bacterial Pathogens 2000 Edition by Kim A Brogden, Es A Roth, Thaddeus B Stanton
The field of microbial pathogenesis has expanded rapidly over the past decade. Literally thousands of research papers have been published and new specialty journals on microbial pathogenesis have appeared, giving rise to the need for a text that reviews the entire field of bacterial virulence mechanisms and summarizes the major advances.The third edition of this best-selling volume provides an overview of current knowledge of the wide variety of mechanisms used by bacterial pathogens in establishing infection, producing disease, and persisting in the host. Internationally recognized authorities in the field review bacterial invasion, colonization, and survival bacterial evasion of host defense mechanisms bacterial effects on host cell function and identification, regulation, and transfer of virulence genes. The final chapter presents an interesting examination of new methods for studying virulence mechanisms in the complex in vivo environment, a major development in studies of bacterial pathogenicity. The overall emphasis is on understanding the mechanisms of host-pathogen interactions rather than on focusing on specific research approaches. Virulence Mechanisms of Bacterial Pathogens, 3rd Edition is valuable reading for molecular biologists, infectious disease specialists, researchers, industry scientists, faculty, and graduate students. Table of contents : - Table of ContentsOrganizing CommitteeContributorsPreface AcknowledgmentsI. Bacterial Invasion, Colonization, and SurvivalSection Editors: James A. Roth and Thad B. Stanton1. Bacterial Adherence, Colonization, and Invasion of Mucosal Surfaces, John H. Brumell and B. Brett Finlay 2. Bacterial Evasion of Host-Derived Antimicrobial Peptides on Mucosal Surfaces, Kim Alan Brogden 3. Consequences of Bacterial Invasion into Nonprofessional Phagocytic Cells, Jeffrey B. Lyczak and Gerald B. Pier 4. Ecological Aspects of Host Colonization: Coaggregation, Osmoadaptation, and Acid Tolerance or Resistance, Thaddeus B. Stanton 5. Relationships between Community Behavior and Pathogenesis in Pseudomonas aeruginosa, Matthew R. Parsek and E.P. Greenberg 6. Antibiotic Resistance and Survival in the Host, Emma L.A. Macfarlane and Robert E.W. HancockII. Bacterial Evasion of Host Defense MechanismsSection Editor: Carole A. Bolin7. What Is the Very Model of a Modern Macrophage Pathogen? David G. Russell 8. Bacterial Resistance to Antibody-Dependent Defenses, Lynette B. Corbeil 9. Mechanisms of Resistance to NO-Related Antibacterial Activity, Andres Vazquez-Torres and Ferric C. Fang 10. DNA Repair and Mutators: Effects on Antigenic Variation and Virulence of Bacterial Pathogens, Thomas A. Cebula and J. Eugene LeClercIII. Bacterial Effects on Host Cell FunctionSection Editor: Michael J. Wannemuehler11. Bacterial Toxins in Disease Production, Joseph T. Barbieri and Kristin J. Pederson 12. Exploitation of Mammalian Host Cell Function by Shigella spp., Larean D. Brandon and Maricia B. Goldberg 13. Bacterial Induction of Cytokine Secretion in Pathogenesis of Airway Inflammation, Alice Prince 14. The Type III Secretion Pathway: Dictating the Outcome of Bacterial-Host Interactions, Raymond Schuch and Anthony T. MaurelliIV. Identification, Regulation, and Transfer of Virulence GenesSection Editor: F. Chris Minion15. Impact of Horizontal Gene Transfer on Evolution of Salmonella Pathogenesis, Robert A. Kingsley, Renee M. Tsolis, Stacy M. Townsend, Tracy L. Norris, Thomas A. Ficht, L. Garry Adams, and Andreas J. Baumler 16. Regulation of Virulence Gene Expression In Vivo, James M. Slauch 17. Identification of Virulence Genes in Silico: Infectious Disease Genomics, George M. Weinstock, Steven J. Norris, Erica J. Sodergren, and David SmajsV. Concluding PerspectiveSection Editor: Kim A. Brogden18. State and Future of Studies on Bacterial Pathogenicity: Impact of New Methods of Studying Bacterial Behavior In Vivo, H. Smith