Description
Elsevier Advances In Protein Chemistry Vol -61 by Volume editor Joel Janin
Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction. Protein Modules and Protein-Protein Interaction: Toward a Global ViewStructural Basis for Affinity and Specificity in Macromolecular RecognitionSequence Analysis of Multidomain Proteins: Past Perspectives and Future Directions Identification of Transiently Interacting Proteins and of Stable Protein Complexes Molecular Recognition in Antibody-Antigen ComplexesMolecular Recognition by SH2 DomainsHow SH3 Domains Recognize Proline Structural Biology of eIF4F: mRNA Recognition and Preparation in Eukaryotic Translation Initiation