Description
LAP Lambert Academic Publishing Antitireoidnye Antitela I Revmatoidnyy Artrit 2012 Edition by Paramonova Ol'ga
Vpervye dlya immunodiagnostiki revmatoidnogo artrita (RA) razrabotana dostupnaya dlya primeneniya v klinicheskikh laboratoriyakh metodika immunofermentnogo opredeleniya urovnya antitel (AT) k tireoidnym gormonam (T3 i T4) na osnove immobilizirovannoy formy magnitoupravlyaemogo sorbenta. V syvorotke krovi bol'nykh revmatoidnym artritom v 45% vyyavleny antitela k T4 i v 39% - antitela k T3. Ikh kontsentratsiya korreliruet s aktivnost'yu patologicheskogo protsessa i prisoedineniem k techeniyu RA patologii shchitovidnoy zhelezy.. Pokazano, chto uroven' AT k T3 i T4 dostoverno otlichaetsya ot soderzhaniya dannykh antitel v syvorotke krovi zdorovykh lits. Vyyavlenie AT k tireoidnym gormonam v predlozhennoy modifikatsii IFA mozhet byt' ispol'zovano v kachestve dopolnitel'nogo testa v kompleksnoy diagnostike pri utochnenii stepeni aktivnosti patologicheskogo protsessa i vydelenii klinicheskikh form RA.