Description
Springer Capsaicin As A Therapeutic Molecule 2014 Edition by Omar M. E. Abdel-salam
This volume provides an up-to-date account of the achievements pertaining to the application of capsaicin and capsaicin-like molecules in the therapy of various human ailments such as pain non-allergic rhinitis obesity tumors and gastrointestinal dermatologic and urologic disorders. It discusses the basic functions of the capsaicin receptor (TRPV1) its mechanisms of action and its role in physiological and pathological processes. The text focuses on the most recent progress in the use of capsaicin and capsaicin-like molecules as a therapeutic agent and highlights potential pharmaceutical implications of further TRPV1 research. The chapters are written by noted experts in their fields of endeavor. This book offers both clinicians and researchers valuable resource and reference material on the subject that will stimulate future research. Table of contents : 1 Capsaicin and Sensory Neurones: a Historical PerspectiveJanos Szolcsanyi2 Pharmacology of the Capsaicin Receptor Transient Receptor Potential Vanilloid Type 1 Ion ChannelIstvan Nagy Dominic Friston Joao Sousa Valente Jose Torres Perez Anna P Andreou3 TRPV1 in the Central Nervous System: Synaptic Plasticity Function and Pharmacological ImplicationsJeffrey G. Edwards4 Topical Capsaicin Formulations in the Management of Neuropathic PainMark Schumacher and George Pasvankas5 Capsaicin-Based Therapies for Pain ControlHoward Smith and John R. Brooks6 Intranasal Capsaicin in Management of Non-allergic (Vasomotor) RhinitisUmesh Singh and Jonathan A. Bernstein7 Capsaicin as an Anti-obesity DrugFelix W. Leung8 The Potential Antitumour Effects of CapsaicinInes Diaz-Laviada and Nieves Rodriguez-Henche9 Capsaicin as New Orally Applicable Gastroprotective and Therapeutic Drug Alone or in Combination with Non-Steroidal Anti-inflammatory Drugs in Human Healthy Subjects and in PatientsGyula Mozsik10 Calcitonin Gene-Related Peptide as Target of Capsaicin Receptor in the GutStefano Evangelista11 Capsaicin for Osteoarthritis PainLaura L. Laslett and Graeme Jones12 The Role of Capsaicin in DermatologyKatherine Boyd Sofia M Shea James W Patterson13 Use of Vanilloids in Urologic DisordersHarris E. Foster Jr. and Ameuro G. Lake