Description
Humana Press Cell Signaling in Vascular Inflammation 1st Editon 2010 Softbound by Jahar Bhattacharya
A comprehensive survey by leading basic and clinical researchers of the signal transduction mechanisms responsible for lung inflammation, including vascular hyperpermeability, white cell accumulation, and vascular remodeling. The authors cut across disciplines to bring together a broad-based presentation of inflammatory challenge, both in the initial phases of the inflammatory response, as well as in the more prolonged phase of genomic involvement. The book illuminates not only the processes of lung inflammation, but also the potential for developing new therapeutic strategies to combat inflammatory lung disease. Heme Oxygenase-1 and Carbon Monoxide in Vascular Regulation.- Tumor Necrosis Factor-?/Receptor Signaling Through the Akt Kinase.- Protein Modifications by Nitric Oxide and Reactive Nitrogen Species.- Redox Signaling in Hypoxic Pulmonary Vasoconstriction.- cGMP-Dependent Protein Kinase in Regulation of the Perinatal Pulmonary Circulation.- Glutamate Receptor Activation in the Pathogenesis of Acute Lung Injury.- Carboxyl Methylation of Small GTPases and Endothelial Cell Function.- Pressure-Induced Inflammatory Signaling in Lung Endothelial Cells.- Regulation of Endothelial Barrier Function.- Sphingolipid Signaling.- Regulation of Cytokine Signaling.- Cell Signaling by Vasoactive Agents.- Reactive Oxygen Species and Cell Signaling in Lung Ischemia.- Pulmonary Vascular Barrier Regulation by Thrombin and Edg Receptors.- Second-Messenger Signaling in Lung Capillaries.- Plasma Membrane-to-Nucleus Calcium Signaling.- Signaling by Mitochondria.- Pro-Inflammatory Signaling by Endothelial Focal Complexes in Lung.- Hydrogen Peroxide As Intracellular Messenger.- Calcium-Inhibited Adenylyl Cyclase (AC6) Controls Endothelial Cell Barrier Function.