Description
LAP LAMBERT Academic Publishing Chastnye Fenomeny Sistemnogo Vospaleniya Pri Spondiloartritakh 2013 Edition by Ivanov Dmitriy, Gusev Evgeniy, Sokolova Lyudmila
Sistemnoe vospalenie - eto tipovoy patologicheskiy protsess, razvivayushchiysya pri sistemnom povrezhdenii i kharakterizuyushchiysya total'noy vospalitel'noy reaktivnost'yu endoteliotsitov, plazmennykh i kletochnykh faktorov krovi, soedinitel'noy tkani, i mikrotsirkulyatornymi rasstroystvami v zhiznenno vazhnykh organakh i tkanyakh. Priznaki sistemnogo vospaleniya vyyavlyayutsya ne tol'ko pri ostrykh septicheskikh sostoyaniyakh, no i pri khronicheskikh autoimmunnykh zabolevaniyakh. V dannoy rabote patogenez spondiloartritov rassmatrivaetsya s tochki zreniya ucheniya o sistemnom vospalenii, kak tipovom patologicheskom protsesse. Ustanovleno, chto pri spondiloartritakh vstrechayutsya tri varianta vospalitel'nogo otveta: klassicheskoe vospalenie s isklyuchitel'no mestnymi proyavleniyami, klassicheskoe vospalenie s sistemnoy vospalitel'noy reaktsiey i khronicheskoe sistemnoe vospalenie. Opredeleny chastoty vstrechaemosti chastnykh fenomenov sistemnogo vospaleniya pri izuchaemykh zabolevaniyakh. Vpervye proveden sravnitel'nyy analiz ekspressii tsitokinov i belkov ostroy fazy, a takzhe rasprostranennosti osnovnykh chastnykh fenomenov sistemnogo vospaleniya pri ankiloziruyushchem spondilite i khronicheskoy forme reaktivnogo artrita.