Description
Elsevier India Cocaine Abuse:Behavior Pharmacology & Clinical Applications by Stephen T. Higgins Jonathan L. Katz
Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems including the spread of infectious disease crime violence and neonatal drug exposure. Cocaine abuse results from a complex interplay of behavioral pharmacological and neurobiological determinants. While a complete understanding of cocaine abuse is currently beyond us significant progress has been made in preclinical research on fundamental determinants of this disorder. These advances are critically reviewed in the first section of this volume. Important advances also have been made in characterizing the clinical pharmacology of cocaine and those advances have been extended to understanding individual vulnerability to cocaine abuse development of effective treatments and discussions of policy. Those advances are critically reviewed in the third section of this volume. Contributors to the book were selected because of their status as internationally recognized leaders in their respective areas of scientific expertise. Moreover each is a proponent of the importance of a rigorous interdisciplinary scientific approach to effectively addressing the problem of cocaine abuse. As such this volume offers a coherent empirically-based conceptual framework for addressing cocaine abuse that has continuity from the basic research laboratory through the clinical and policy arenas. Each of the specific chapters is sufficiently detailed in-depth and current to be valuable to informed readers with specific interests while also offering a comprehensive overview for those who might be less informed or have broader interests in cocaine abuse. This blend of critical review within each chapter with an explicitly conceptual continuity that spans all of the chapters makes this volume a unique contribution to cocaine abuse in particular and substance abuse in general.