Description
John Wiley Concepts In Biology - A Historical Perspective by Marc Gilbert
This book provides a comprehensive review of the history of concepts of the endocrine nervous and immune systems throughout the last century.Historically these systems were long considered as compartments that performed separate and different functions. However a breakthrough occurred when advances in genetics and cellular and molecular biology techniques revealed that these systems shared molecular entities (such as cytokines hormones and neurotransmitters) with their cognate receptors.These molecular links between the three systems broaden our understanding of the regulation of physiological processes. This approach has generated a multiplicity of new concepts including crosstalk between organs axis feedback molecular sensors protein multi-functionality positive and negative signaling ratios and pathways (such as cell signaling metabolism and stem cell differentiation to name a few).The improvement of experimental approaches has often resulted in major discoveries. This combined with clear reasoning intuition and coherence gave rise to new and unexpected concepts and sometimes evolving ones. These new concepts lead the reader to the incredible transformation of biology in recent years.