Description
Springer Drosophila Models For Human Diseases 2018 Edition by Masamitsu Yamaguchi
Most biological pathways, physical and neurological properties are highly conserved between humans and Drosophila and nearly 75% of human disease-causing genes have a functional homologue in Drosophila. This volume provides recent advances in Drosophila models for various human diseases, with each chapter providing a review of studies involving Drosophila models, as well as detailed protocols commonly used in laboratories. Starting with a review of Drosophila's value as a highly tractable model organism for studying human diseases, subsequent chapters present Drosophila models for specific human diseases.The book provides a useful resource for all scientists who are starting to use the Drosophila model in their studies, and for researchers working in the pharmaceutical industry and using new screening models to develop new medicines for various diseases. Table of contents : Ch1 Drosophila as a model organismMasamitsu Yamaguchi, Hideki Yoshida, Department of Applied Biology, Kyoto Institute of TechnologyCh2 Adult intestine aging modelTakashi Okumura, Koji Takeda, Takashi Adachi-Yamada, Gakushuin UniversityCh3 Alzheimer's disease modelLeo Tsuda, National Center for Geriatrics and Gerontology (NCGG)Ch 4 Parkinson's disease modelDang Thi Phuong Thao, University of Science, Vietnam National University, Ho Chi Minh CityChapter 5Repeat expansion disease modelMorio Ueyama, Yoshitaka Nagai, Osaka UniversityCh6 Amyotrophic lateral sclerosis modelYumiko Azuma, Takahiko Tokuda, Kyoto Prefectural University of MedicineCh7 Charcot-Marie-Tooth disease modelMasamitsu Yamaguchi, Hiroshi Takashima, Kyoto Institute of Technology, Kagoshima UniversityCh8 Role of long non-coding RNA in neurological diseasesLuca Lo Piccolo, Kyoto Institute of TechnologyCh9 Muscular dystrophy modelSaranyapin Potikanond, Wutigri Nimlamool, Jasprien Noordermeer, Lee FradkinChiang Mai University, Molecular biology department, Leiden University Medical Center (LUMC), Department of Neurobiology, UMass Medical SchoolCh10 Cancer modelTatsushi Igaki, Kyoto UniversityCh11 Leukemia modelLucas Waltzer, Centre de Biologie du Developpement, CNRS - Universite Paul Sabatier, Toulouse, FranceCh12 Diseases of replication /repair genesSue Cotterill, St Georges University of LondonCh13 Drosophila models for studying UPR in insulin-like peptide producing cells and onset of type I diabetesYoshihiro H. Inoue, Insect Biomedical Research Center, Kyoto Institute of TechnologyCh14 Metabolomics study on Drosophila modelsPhan Nguyen Thuy An, Eiichiro Fukusaki, Graduate School of Engineering, Osaka UniversityCh15 Humanized flies for functional analysis of the human genome and cross-species comparisonToshiyuki Takano-Shimizu, Department of Drosophila Genomics and Genetic Resources, Kyoto Institute of TechnologyCh16 Designs for FliesFrank Kolkman, Julia Cassim, Royal College of Arts, Kyoto Institute of Technology