Description
Taylor & Francis Ltd Drug Trials In Epilepsy: A Physician'S Guide by Dieter Schmidt
With the proliferation of antiepileptic drugs over the last decade, clinicians are increasingly looking for guidance from clinical trials to help them decide the best drug to treat an individual suffering from epilepsy As there are different trials for different purposes and regulatory guidelines can differ from country to country, there is a bewildering array of guidelines This book offers a guide of drug trials in epilepsy in an effort to help clinicians choose the best drugs for their patients. Table of contents
The need for controlled trials; current standards for clinical testing of new antiepileptic drugs; placebo controlled add-on trials; placebo controlled monotherapy trials in early epilepsy; presurgical trials; attenuated active controlled trials; dose responsive trials; fully dosed active controlled trials; randomized unblinded trials; the ethics of clinical testing; the regulatory relevance of randomized controlled trials; the clinical usefulness of randomized controlled trials; development plans for new antiepileptic drugs; guidelines for clinical testing of new antiepileptic About Dieter Schmidt
[MD] - Professor and Head of the Epilepsy Research Group, Berlindrugs (ILAE, EU, FDA).