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Humana Early Clinical Intervention And Prevention In Schizophrenia by William S. Stone , Stephen V. Faraone , Ming T. Tsuang
Leading and internationally recognized researchers review what is known about the liability to schizophrenia, how it progresses, what it looks like clinically-with an emphasis on a specific (proposed) syndrome of liability (schizotaxia)-and how best it might be treated now and in the near future. The authors summarize the latest findings on the genetic, early environmental, and neurodevelopmental origins of schizophrenia. Part I. The Etiology and Genetics of SchizophreniaThe Genetic Basis of SchizophreniaStephen V. Faraone, Stephen J. Glatt, and Levi TaylorEarly Environmental Determinants of SchizophreniaJason Schiffman, John Carter, Ricardo A. Machon, and Sarnoff MednickObstetric Risk Factors for Schizophrenia and Their Relationship to Genetic Predisposition: Following Ariadne's Double-Stranded Thread Through Early DevelopmentStefano Marenco and Daniel R. WeinbergerPart II. The Vulnerability to SchizophreniaThe Nature of the Prodrome in SchizophreniaJaak Rakfeldt and Thomas H. McGlashanThe Nature of SchizotaxiaStephen V. Faraone, Ming T. Tsuang, and Sarah I. TarboxA Neuropsychological Perspective on Vulnerability to Schizophrenia: Lessons From High-Risk StudiesAllan F. Mirsky and Connie C. DuncanNeurocognitive Deficits in the Biological Relatives of Individuals With SchizophreniaWilliam S. Kremen and Anne L. HoffThe Nature and Origin of Socioemotional Deficits in SchizophreniaElaine Walker and Karen M. HochmanNeuroimaging Studies of Nonpsychotic First-Degree Relatives of People With Schizophrenia: Toward a Neurobiology of Vulnerability to SchizophreniaLarry J. Seidman, Heidi E. Wencel, Colm McDonald, Robin M. Murray, and Ming T. TsuangNeurophysiological Endophenotypes in Early Detection of SchizophreniaMarina Myles-WorsleyIs the Development of Schizophrenia Predictable?Paola Dazzan, Eugenia Kravariti, Paul Fearon, and Robin M. MurrayPart III. Early Intervention and Prevention of SchizophreniaPrevention of Schizophrenia and Psychotic Behavior: Definitions and Methodological IssuesC. Hendricks Brown and Stephen V. FaraoneThe Treatment of SchizotaxiaMing T. Tsuang, Sarah I. Tarbox, Levi Taylor, and William S.StoneTreatment of the Schizophrenia ProdromeBarbara Cornblatt, Todd Lencz, Christopher Smith, and Andrea AutherThe Role of Genetic CounselingDebby W. Tsuang, Stephen V. Faraone, and Ming T. TsuangPart IV. Challenges for the Near FutureThe Biology of SchizotaxiaWilliam S. Stone, Stephen J. Glatt, and Stephen V. FaraoneMolecular Medicine and the Prospects for Prevention and Early Intervention in SchizophreniaWilliam T. Carpenter, Jr. and James I. KoenigIndex