Description
Taylor & Francis Endocrine Therapy in Breast Cancer 2002 Edition by William R. Miller, James N. Ingle
This reference evaluates and describes the latest strategies for hormone suppression and blockade in the management of early and advanced stage breast cancer and explores the effects of tamoxifen, selective estrogen receptor modulators (SERMs), aromatase inhibitors, and their combination on both breast cancers and normal tissues.Endocrine Therapy in Breast Cancer details modern techniques for molecular profiling, monitoring, and targeting offers methods to identify high-risk groups evaluates molecular biomarkers in breast cancer assessment examines the potential toxicity of estrogen receptor (ER)-directed endocrine therapy investigates the development of endocrine resistance discusses neoadjuvant and preoperative approaches in patient care reviews mechanisms that lead to estrogen-independent phenotypesSurveying the medical, surgical, and pathological aspects of endocrine therapy, as well as future research opportunities, Endocrine Therapy in Breast Cancer is a concise and in-depth manual for medical, surgical, and radiation oncologists endocrinologists gynecologists obstetricians pharmacologists family physicians reproductive biologists epidemiologists and medical school students. Table of contents :- IntroductionWhy Endocrine Therapy?Daniel F. HayesAdvanced Breast CancerTamoxifen and Advanced Breast Cancer: An OverviewJohn F. ForbesOverview of Aromatase Inhibitors and Inactivators in the Treatment of Advanced Breast CancerPer Eystein LonningEndocrine Treatment of Advanced Breast Cancer-Selective Estrogen-Receptor Modulators (SERMs)Stephen R. D. Johnston and Anthony HowellOther Endocrine and Biological Agents in the Treatment of Advanced Breast Cancer