Description
Apple Academic Press Inc. Fundamentals of Asymmetric Synthesis 2014 Edition by G. L. David Krupadanam
Asymmetric synthesis is an integral part of synthetic organic chemistry. Some of the reactions in this book were known prior to 1980, while several new ones, particularly catalytic asymmetric reactions, have been discovered in the recent years. The impact of this new class of reactions has been impressively extensive-both on organic and medicinal chemistry. These reactions have been accepted whole-heartedly by synthetic organic chemists in developing shorter routes for complex natural targets as well as in the manufacture of a wide range of drug intermediates. Table of contents :- IntroductionTerms, Definitions and Concepts in Asymmetric SynthesisAchiral and Chiral Molecules and Their PropertiesProchiralityEnantioselective and Diastereoselective SynthesisMethods for Monitoring Enantioselective and Diastereoselective SynthesisMethods for Inducing AsymmetryChiral Substrate Controlled Asymmetric Reactions: Diastereoselection in acyclic systemsChiral auxiliary controlled asymmetric reactions-Asymmetric -alkylationsChiral Stoichiometric Reagent Controlled Asymmetric Synthesis: Chiral Boron ReagentsChiral Catalyst Mediated Asymmetric Reactions: EnzymesChiral Organometallic Catalysed Asymmetric Reactions: Sharpless Asymmetric Epoxidations, Dihydroxylations and AminohydroxylationsChiral Organometallic Catalysed Asymmetric ReactionsOrganocatalysts in Asymmetric Synthesis-Chiral Additive Mediated ReactionsAsymmetric Aldol ReactionAsymmetric Diels-Alder reactionsStereoselective Synthesis and Stereospecific SynthesisIndex