Description
ELSEVIER Handbook Of Glycomics by Cummings
The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans. Introduction to GlycomicsSECTION 1: Glycoconjugate Structural Analysis 1. Glycoproteomics: N-glycan Analysis 2. Glycoproteomics: O-glycan Analysis 3. Glycosaminoglycans 4. Isotopic Labeling of Glycans for Quantitative Glycomics SECTION II: Glycotranscriptomics 5. Glycotranscriptomics SECTION III: Protein-Glycan Interactions 6. Glycan Arrays 7. Chromatographic and Mass Spectrometric TechniquesSECTION IV: Glycobioinformatics8. Integration of Glycomics Knowledge and Data9. KEGG GLYCAN for integrated analysis of pathways, genes, and glycan structures10. European Glycomics Portal SECTION V: Glycomes11. Glycomics of the Immune System12. Mouse and Human13. Drosophila14. Malaria15. Parasitic WormsSECTION VI: Disease Glycomes16. Cancer Glycomics17. An Introduction to Human Disorders of Glycosylation18. Summary