Description
Springer Handbook On Analyzing Human Genetic Data Computational Approaches And Software 2009 Edition by Shili Lin Hongyu Zhao
This handbook offers guidance on selections of appropriate computational methods and software packages for specific genetic problems. Coverage strikes a balance between methodological expositions and practical guidelines for software selections. Wherever possible comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches. Table of contents : Population Genetics.- Haplotype Structure.- Linkage Analysis of Qualitative Traits.- Linkage Analysis of Quantitative Traits.- Markov Chain Monte Carlo Linkage Analysis Methods.- Population-Based Association Studies.- Family-Based Association Studies.- Haplotype Association Analysis.- Multiple Comparisons/Testing Issues.- Estimating the Absolute Risk of Disease Associated with Identified Mutations.- Processing Large-Scale High-Dimension Genetic and Gene Expression Data.