Description
Taylor & Francis Handbook of Multiple Sclerosis Third Edition 2001 by Stuart D. Cook
Reporting on the latest advances made in treating multiple sclerosis (MS) and continuing the high standards set by earlier editions, the Handbook of Multiple Sclerosis, Third Edition examines a wide range of topics from etiology to treatment options. Analyzes recent developments in the natural history, immunopathology, lesion evolution, and therapy affecting MS treatment-including up-to-date research results from experimental therapies with t-cell vaccines, oral myelin, and monoclonal antibodies!Summarizing previous breakthroughs and pointing the way toward future research, the Handbook of Multiple Sclerosis, Third Editionprovides a historical summary of the disease and examines the epidemiology and genetics of MS, including new evidence for and against an infectious etiology investigates virus-induced demyelination, emphasizing models such as canine distemper (CDV), corona, visna, and herpes simplex viruses; the semliki forest virus (SFV); and animal models of autoimmune demyelination notes the role of magnetic resonance imaging (MRI) in diagnosis, prognosis, natural history, and as a guide to therapy explores the growing evidence for axonal damage as a major cause of disability in MS summarizes the natural history of MS and delineates factors influencing exacerbations and progression of the disease assesses current clinical and biological prognostic indicators for accurate diagnoses of MS as opposed to other idiopathic inflammatory demyelinating diseases (IIDDs) and evaluates the growing number of therapies for treating MS and more! Table of contents : - EtiopathogenesisThe History of Multiple SclerosisW. I. McDonaldThe Epidemiology of Multiple SclerosisWilliam Pryse-Phillips and Fiona CostelloThe Genetics of Multiple SclerosisJan Hillert and Thomas MastermanExperimental Models of Virus-Induced DemyelinationMauro C. Dal CantoEvidence for a Viral Etiology of Multiple SclerosisStuart D. CookExperimental Models of Autoimmune DemyelinationFred D. LublinEvidence for ImmunopathogenesisUte TraugottAutoantibodies in Demyelinating DiseaseAnne H. Cross, Jeri-Anne Lyons, and John L. TrotterClinical Pathologic FeaturesClinical FeaturesAaron E. MillerCognitive Impairment in Multiple SclerosisJill S. FischerLoss and Restoration of Impulse Conduction in Disorders of MyelinStephen G. WaxmanPathology of Multiple SclerosisJohn W. PrineasAxonal Injury in Multiple SclerosisCarl Bjartmar and Bruce D. TrappCerebrospinal FluidJohn N. Whitaker, Khurram Bashir, and Etty N. BenvenisteLaboratory Tests: Evoked PotentialsMarc R. NuwerNeuroimaging and the Use of Magnetic Resonance in Multiple SclerosisLael A. Stone, Nancy Richert, and Henry McFarlandTherapeutic ConsiderationsThe Natural History of Multiple SclerosisSandra Vukusic and Christian ConfavreuxPrognostic Factors in Multiple SclerosisOrhun H. Kantarci and Brian G. WeinshenkerTherapeutic Considerations: Rating ScalesRichard Rudick, Brian Weinshenker, and Gary CutterTherapeutic Considerations: Treatment of the Acute ExacerbationRaymond TroianoInterferon- -1b: Prophylactic Therapy in Multiple SclerosisKenneth P. Johnson and Peter A. CalabresiTherapeutic Considerations: Prophylactic Therapy with Interferon- -1aLawrence JacobsProphylactic Therapy-Glatiramer Acetate (Copaxone (R))Hillel PanitchTreatment of Multiple Sclerosis with Intravenous ImmunoglobulinP. RudgeImmunosuppressive DrugsMariko Kita and Donald E. GoodkinTreatment of Multiple Sclerosis: Bone Marrow Reconstitution, Total Lymphoid Irradiation, and Plasma ExchangeGeorge P. A. RiceSymptomatic TherapyRandall T. SchapiroSymptomatic Treatment and Rehabilitation in Multiple SclerosisCharles R. Smith and Labe ScheinbergExperimental Therapies with T-Cell Vaccines, Oral Myelin, and Monoclonal Antibodies in Multiple SclerosisSuprabha Bhat and Jerry S. WolinskyFuture ImmunotherapiesChristine Rohowsky-Kochan