Description
Oxford Handbook of Physiology Cell Physiology Section 14 1997 Edition by Joseph F. Hoffman, James D. Jamieson
The aim of this Handbook is to survey the foundations and current status of key areas in modern cellular and molecular physiology. The topics covered range from the most fundamental biophysical and biochemical bases of cellular physiology to more concerted cellular biological pro-cesses. A more elusive goal of this volume is to provide a framework for future research linking these various processes with their integrative aspects in whole animal systems. The chapters begin with basic membrane processes that include membrane structure as it relates to function, the biophysics of membrane transport, and cell volume regulatory mechanisms. Then the organization and function of the plasma membrane and intracellular organelles involved in membrane trafficking and the biogenesis of cell polarity are reviewed in depth. Energy generation and transduction that subserve cellular function are covered in another series of chapters. The structure and function of the cytoskeleton and its relationship to events regulated by interaction with the extracellular matrix are examined in detail.Chapters on integrative aspects of cellular physiology including immunobiology, cell-cell interactions, fertilizaton, and interactions of cells with the extracellular matrix round out the authoritative survey of contemporary cellular physiology in the Hand-book. Researchers, teachers, and graduate students will find it a uniquely useful resource. Table of contents : - 1. Optical Methods and Image Analysis in Cell Physiology; 2. Organization and Dynamics of the Lipid Components of Biological Membranes; 3. Membrane Structure/Proteins; 4. Energy Transduction Mechanisms (Animals and Plants); 5. Principles of Regulation and Control in Biochemistry; A Pragmatic, Flux-Oriented Approach; 6. Basic Principles of Transport; 7. Membrane Transport in Single Cells; 8. Epithelial Transport; 9. Intracellular pH; 10. Osmolytes and Cell Volume Regulation: Physiological and Evolutionary Principles; 11. Cytoskeletal Membrane Interactions; 12. Extracellular Matrix: A Solid-State Regulator of Cell Form, Function and Tissue Development; 13. Microtubule Motors in Cell and Tissue Function; 14. Membrane Fusion; 15. Membrane ER Golgi Events; 16. Regulated Exocytosis in Mammalian Secretory Cells; 17. Epithelial Cell Polarity: Challenges and Methodologies; 18. The Switch and Assembly Paradigms of Transmembrane Signaling; 19. Cellular Immunology; 20. Cilia and Related Microtubular Arrays in the Eukaryotic Cell; 21. Principles of Cell Cycle Control; 22. Regulation of Development: Differentiation and Morphogenesis; 23. Activation of Sperm and Egg during Fertilization; 24. Cellular Mechanisms during Mammalian Fertilization