Description
Wiley-VCH Verlag GmbH Immunodominanace The Choice Of The Immune System 2006 Edition by Jeffrey A. Frelinger
This very first handbook on the topic summarizes the current concepts and brings together in one volume the critical arguments concerning the mechanisms relevant to immunodominance. In invited chapters written by the leaders in the field, the mechanisms whereby the immune system chooses the parts of a recognized pathogen in order to start the immune response are explained and the variety of biologic processes are identified that contribute to that choice. From the contents: Mechanics of antigen processing Proteosome specificity and immuno-proteosomes Effect of the T cell repertoire on dominance Effects of pathogens on the immune response