Description
Taylor & Francis Ltd Introduction To Natural Products Chemistry 2011 Edition by Rensheng Xu, Yang Ye, Weimin Zhao
Natural products chemistry-the chemistry of metabolite products of plants, animals and microorganisms-is involved in the investigation of biological phenomena ranging from drug mechanisms to gametophytes and receptors and drug metabolism in the human body to protein and enzyme chemistry. Introduction to Natural Products Chemistry has collected the most important research results of natural product chemistry in China. It overviews the basic principles of isolation, structure, and characteristics of natural products and illustrates current research techniques of structure elucidation with real-life examples of wet chemistry and spectroscopic analyses (UV, IR, MS, and NMR, especially 2d-NMR, HMBC, and HMQC), bioactivity, biosynthesis, and chemical synthesis. Specifically, this book covers:Extraction and isolation of natural productsChemistry of fungal productsAlkaloids, sesquiterpenoids, diterpenes, and saponinsAmino acids and peptidesFlavonoids, anthraquinones, coumarins, and lignansMarine natural productsStructural modification of active principles from traditional Chinese medicineChemical synthesis of natural productsAlthough natural products chemistry has produced enormous results and made great contributions to human health, industry, and agriculture, only a fraction of natural resources have been rigorously studied. Chinese natural products are a gold mine for further exploration with modern technology and methods. This book represents the continuing collaboration between the fields of natural products chemistry, medicine, biology, and agriculture which will continue to discover and implement novel chemical products from natural sources. Introduction, Ren-Sheng XuExtraction and Isolation of Natural Products. Ren-Sheng XuExtraction of Natural ProductsSeparation of Natural ProductsConcluding RemarksBibliographyReferencesChemistry of Fungal Products, Zhi-Hong XuIntroductionBioactive Fungal MetabolitesMycotoxins from FungiIsolation and Structure Studies of Fungal ProductsPerspectivesReferencesAlkaloids, Ren-Sheng Xu and Yang YeGeneralCharacterization, Identification and IsolationClassificationStructural Investigations of Some Alkaloids BibliographyReferencesSesquiterpenoids, Zhong-Liang ChenChemical Properties, Isolation and Purification Spectroscopic Analysis of Sesquiterpenes Artemisinin - Chemistry, Pharmacology, and Clinical Uses Recent Progress of Specific Sesquiterpenes References Diterpenes, Zhi-DaMinMain Diterpene Skeletons Biogenesis Labdanes Clerodanes Pimaranes Abietanes Cassanes and TotaranesTaxanes Tiglianes, Ingenanes and DaphnanesJatrophanes and Lathyranes Myrsinols and Euphorsctines Ginkgolides and Pseudolaric Acid ReferencesSaponins, Wei-Min ZhaoIntroductionExtraction and Isolation of Saponins Structure Determination of Saponins Biological Activity of Saponins Triterpenoid Saponin Steroidal SaponinsBibliography ReferencesAmino Acids and Peptides, Chang-Qi Hu and Jie-Cheng XuAmino Acids Peptides ReferencesFlavonoids, De-Yun KongOverview Extraction and Isolation of Flavonoids Identification and Structure Study of Flavonoids Pharmacological Study of Flavonoids Flavonoids Assay Determination and Formulation Conclusion ReferencesAnthraquinones, Yang LuIntroductionPhysical and Chemical PropertiesExtraction and Isolation Spectral CharacteristicsExamples ReferencesCoumarins, Ze-Nai ChenIntroductionStructural Types Physical and Chemical PropertiesIsolationSpectroscopic Identification Research ExampleReferencesLignans, Chang-Qi HuIntroductionStructural Types and Characteristics of Lignans Bioactivities of Lignans ReferencesOther Natural Bioactive Compounds, Ren-Seng XuSulfur CompoundsCyanide Compounds Coixenolide Resveratrol Muscone Cardiac GlycosidesBibliography ReferencesMarine Natural Products, Yue-Wei Guo and Wen ZhangIntroductionMarine PlantsMarine Invertebrates Marine Microorganisms and Phytoplankton MiscellaneousExamples Epilogue (Outlook) References Structural Modification of Active Principles from TCM, Da-Yuan ZhuIntroductionAnti-malaria Drug Arthemether Anti-hepatitis Drug Bifendate Anti-AD Drug Huperzine A Antiarrhythmia Drug Changrolin Antineoplastic Drugs Computer-Aided Drug Design ReferencesChemical Synthesis of Natural Products, Wen-Hu DuanAlkaloidsTerpene Flavonoids Synthesis of Anthraquinones Lignans Synthesis of Macrolide AntibioticsBibliography References