Description
LAP LAMBERT Academic Publishing Izmeneniya v serdechno-sosudistoy sisteme 2011 Edition by Rasulov M, Namakanov B
Izuchena problema semeynoy arterial'noy gipertenzii. Provedeno klinicheskoe issledovanie adaptivnykh vozmozhnostey serdechno- sosudistoy sistemy, sostoyanie diastolicheskoy funktsii serdtsa i uroven' arterial'nogo davleniya u 1500 bol'nykh. Vyyavleno, chto u normotenzivnykh rodstvennikov s semeynoy arterial'noy gipertenziey chashche nablyudalis' izmeneniya transmitral'nogo krovotoka, svoystvennye diastolicheskoy disfunktsii levogo zheludochka, po sravneniyu s normotonikami bez nasledstvennoy otyagoshcheniya po arterial'noy gipertenzii. Izmeneniya transmitral'nogo krovotoka svidetel'stvovali o zamedlenii aktivnogo rasslableniya i povyshenii zhestkosti polosti LZh, t.e. snizhenii diastolicheskikh svoystv levogo zheludochka i kharakterizovalis' pereraspredeleniem krovotoka v pol'zu predserdnoy sistoly po sravneniyu s kontrol'noy gruppoy. Ukhudshenie diastolicheskikh svoystv levogo zheludochka obuslovleno rannim formirovaniem gipertrofii miokarda levogo zheludochka, privodyashchey k snizheniyu elastichnosti miokarda i umen'sheniyu podatlivosti ego kamery. Opredeleny vozmozhnosti korrektsii narusheniy diastolicheskoy funktsii levogo zheludochka s pomoshch'yu ingibitorov angiotenzin-prevrashchayushchego fermenta.