Description
Palmarium Academic Publishing Khronicheskaya Obstruktivnaya Bolezn Legkikh 2014 Edition by Kuzubova Nataliya, Lebedeva Elena, Titova Ol'ga
Khronicheskaya obstruktivnaya bolezn' legkikh (KhOBL) yavlyaetsya odnoy vedushchikh prichin zabolevaemosti i smertnosti i privodit k znachitel'nomu ekonomicheskomu i sotsial'nomu ushcherbu. V osnove vozniknoveniya i progressirovaniya KhOBL lezhit khronicheskoe vospalenie, kotoroe yavlyaetsya universal'noy reaktsiey na vozdeystvie faktorov riska razvitiya bolezni i glavnoy prichinoy vsekh ee funktsional'nykh i morfologicheskikh proyavleniy. Predstavleno novoe napravlenie v patogeneze KhOBL - rol' sosudistykh i neyrogennykh mekhanizmov v formirovanii etogo zabolevaniya, rassmotreny kletochno-molekulyarnye mekhanizmy, uchastvuyushchie v progressirovanii patologicheskogo protsessa, predlozheny varianty medikamentoznoy korrektsii vyyavlennykh narusheniy. Znachitel'nyy razdel posvyashchen geneticheskim issledovaniyam. Predlozheny diagnosticheskie kriterii effektivnosti kortikosteroidnoy terapii pri KhOBL. Opisana eksperimental'naya model' KhOBL i pokazany vozmozhnosti ee primeneniya dlya nauchnykh issledovaniy. Kniga prednaznachena dlya pul'monologov, terapevtov razlichnoy spetsializatsii, vrachey-issledovateley.