Description
LAP LAMBERT Academic Publishing Laboratornye Markery Endotelialnoy Disfunktsii 2012 Edition by Kiprina Elena, Berns Svetlana
Ser'eznoe vnimanie pri izuchenii patogeneza ishemicheskoy bolezni serdtsa udelyaetsya disfunktsii endoteliya - kak naibolee ranney fazy povrezhdeniya sosudistoy stenki. Kazhdaya iz funktsiy endoteliya, opredelyayushchaya trombogennost' sosudistoy stenki, vospalitel'nye izmeneniya, vazoreaktivnost' i stabil'nost' ateroskleroticheskoy blyashki, napryamuyu ili kosvenno svyazana s progressirovaniem ishemicheskoy bolezni serdtsa i ee oslozhneniy. V dannoy rabote byla opredelena patogeneticheskaya svyaz' faktorov vospaleniya, endotelial'noy disfunktsii, trombotsitarnogo i koagulyatsionnogo gemostaza u bol'nykh s ostrym koronarnym sindromom, podvergshikhsya chreskozhnym koronarnym vmeshatel'stvam. Vpervye byla provedena sravnitel'naya kompleksnaya otsenka vliyaniya faktorov nespetsificheskogo vospaleniya, endotelial'noy funktsii i gemostaza na razvitie neblagopriyatnykh koronarnykh sobytiy u bol'nykh s razlichnymi variantami ostrogo koronarnogo sindroma, podvergshikhsya chreskozhnomu koronarnomu vmeshatel'stvu.