Description
Taylor & Francis Neurobehavioral Genetics Methods and Applications 1999 Edition by Byron C. Jones, Pierre Mormede
Neurobehavioral Genetics: Methods and Applications covers classic and contemporary approaches to the study of the brain and behavior, including basic and clinical research. This book is designed as a reference for investigators wishing to incorporate genetic methods into neurobehavioral research. A broad spectrum of methods are integrated, unlike any other publication currently in print. Neurobehavioral Genetics: Methods and Applications presents different models, from invertebrates to genetically defined mammals. Introductory chapters demonstrate the scope and power of genetic methods that can be applied to neurobehavioral research from statistical methods and linkage analysis to contemporary molecular genetic approaches to search for candidate genes.The second half of the book covers the applications of quantitative and molecular genetics in basic and clinical research. Topics covered include animal behavior and neurobiology and human clinical problems including neurodegenerative diseases and psychiatric disorders. Table of Contents : A Retrospect on Neurobehavioral GeneticsPART 1: BASIC QUANTITATIVE AND STATISTICAL METHODSAn Introduction to Quantitative GeneticsPlanning Genetic Experiments: Power and Sample SizeClassical Linkage AnalysisPART 2: MOVING FROM MATHEMATICS TO GENESNeurogenetics: Mendelian Genetics - Single-Gene Effects and Some of Their Complicating FactorsQuantitative Trait Loci (QTL) MappingFrom QTL Detection to Gene Identification-M. P. MoisanKnockouts: Constitutive, Inducible, or Tissue Specific. The Example of 5-HT Receptors-R. Grailhe and R. HenPART 3: ANIMAL MODELSBehavioral Phenotyping of Transgenic and Knockout Mice-J. N. CrawleyAnimal Models in Neurobehavioral Genetics: Methods for Estimating Genetic Correlation - John C. CrabbePART 4: HUMAN METHODSHuman Family Studies-L. M. KarkowskiThe Twin Method-M. Carlier and E. SpitzPART 5: GENE-ENVIRONMENT INTERACTIONS AND MATERNAL EFFECTSDetecting and Measuring Gene-Environment Interaction in Human Temperament (Aggressivity) and Personality Deviation (Conduct Disorder, Antisocial Personality)-K. Riggins-Caspers and R. J. CadoretMaternal Effects in Behavior Genetic Analysis-M. Carlier, P. Roubertoux, and D. WahlstenPART 6: METHODS AND APPLICATIONS IN NEUROGENETICSCerebellar Functions: A Behavioral Neurogenetic Perspective-L. Rondi-Reig, J. Caston, N. Delhaye-Bouchaud, and J. MarianiNatural Genetic Variation of Hippoccampal Structures and Behavior-H. P. Lipp and D. P. WolferHuman Neurogenetics: Neurodegenerative Diseases-A. D. DurrPART 7: PSYCHIATRIC GENETICSSchizophrenia: Study of a Genetically Complex Phenotype-M. F. Pogue-Geile and I. I. GottesmanGenetics of Autism and Its Place in an Integrated Clinicobiological Approach-S. TordjmanGenetic Basis of Mental Retardation-L. ColleauxPART 8: GENETICS OF AGGRESSION AND EMOTIONALITYAggression: Concepts and Methods Relevant to Genetic Analyses n Mice and Humans-S. MaxsonGenetics and Emotional Behaviors: Experimental Studies-P. Mormede and A. Ramos