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Springer Pancreatitis 1st Editon 2011 Softbound by Paul G. Lankisch, Peter A. Banks
As we began to plan this book about 10 years ago, we wanted to write a practical book for medical students, doctors in training, internists, gas and surgeons faced with everyday clinical problems in troenterologists, the care of patients with acute and chronic pancreatitis. Now, 10 years lat er, our book has become much more than what we had originally intend ed, with so many new findings that have expanded our knowledge of pancreatic diseases, not to mention new imaging procedures and con trolled studies on the effectiveness of various therapies. Consequently, we decided to include: • The state-of-the-art on diagnosis and therapy in inflammatory pan creatic diseases • Recommendations for diagnosis and therapy based on the published results from experienced clinicians. In the many areas still untested we have relied on the decades of experience of the two authors on both sides of the Atlantic • A discussion of unanswered questions for future research by physi cians interested in pancreatitis who can draw upon our bibliography of almost 1900 references complete through 1996. We also wanted to demonstrate with this work that two authors from two continents can come to common conclusions that can help physicians and students in their everyday clinical work and their clinical research. It is with deep gratitude that we acknowledge the assistance of Mrs. Gisela Ropte for years of patient cooperation, great precision, and initia tive, as well as that of Dr. Dr. 1 General Considerations: Embryology.- 1.1 Normal Development.- 1.2 Congenital Abnormalities.- References.- 2 General Considerations: Anatomy.- References.- 3 General Considerations: Physiology.- 3.1 Function of the Exocrine Pancreas.- 3.2 Pancreatic Enzymes.- 3.3 Enzyme Synthesis.- 3.4 Protective Mechanisms to Prevent Autodigestion.- 3.5 Pancreatic Secretagogues.- 3.6 Phases of Pancreatic Secretion.- 3.7 Ductular Secretion.- 3.8 Acinar Secretion.- 3.9 Action of Pancreatic Lipase.- 3.10 What Turns the Pancreas Off?.- References.- 4 General Considerations: Classification.- 4.1 Marseille Classification of 1963.- 4.2 Cambridge Classification of 1983.- 4.3 Revised Pancreatitis Classification of Marseille 1984.- 4.4 Pancreatitis Classification of Marseille-Rome 1988.- 4.5 Pancreatitis Classification — Cambridge vs. Marseille: Features in Common and Differences.- 4.6 Classification System for Acute Pancreatitis of Atlanta 1992.- 4.7 Comment.- References.- 5 Acute Pancreatitis: Etiology.- 5.1 Biliary Tract Disease.- 5.2 Alcoholism.- 5.3 Obstruction of Pancreatic Ducts.- 5.4 Infections.- 5.5 Drugs.- 5.6 Toxins.- 5.7 Endocrine and Metabolic Disorders.- 5.8 Vascular Disease.- 5.9 Trauma.- 5.10 Medical Procedures.- 5.11 Surgical Procedures.- 5.12 Cystic Fibrosis.- 5.13 Inborn Errors of Metabolism.- 5.14 Reye’s Syndrome.- 5.15 Kawasaki Disease.- 5.16 Hereditary Acute Pancreatitis.- 5.17 Idiopathic Acute Pancreatitis.- References.- 6 Acute Pancreatitis: Pathophysiology.- 6.1 Mechanisms of Pancreatic Injury.- 6.2 Gallstone-induced Acute Pancreatitis.- 6.3 Alcohol-induced Acute Pancreatitis.- 6.4 Concept of Oxidative Stress.- 6.5 Theories Explaining the Pathogenetic Mechanism of Acute Biliary Pancreatitis.- 6.6 The Pros and Cons of the Theories.- References.- 7 Acute Pancreatitis: Pathology.- 7.1 Gross Pathology.- 7.2 Histopathology.- 7.3 Sequential Changes and Outcome.- References.- 8 Acute Pancreatitis: Epidemiology.- References.- 9 Acute Pancreatitis: Diagnosis.- 9.1 Clinical Manifestation.- 9.2 Laboratory Investigations.- 9.3 Imaging Procedures.- 9.4 Synopsis of Diagnostic Procedures and Grading of Severity.- References.- 10 Acute Pancreatitis: Complications.- 10.1 Local Complications.- 10.2 Systemic and Other Extrapancreatic Complications.- References.- 11 Acute Pancreatitis:Treatment.- 11.1 Basic Treatment.- 11.2 Treatment of Local Complications.- 11.3 Treatment of Systemic Complications.- 11.4 Treatment of Metabolic Complications.- 11.5 Treatment of Extrapancreatic Complications.- References.- 12 Acute Pancreatitis: Prognosis.- 12.1 Introduction.- 12.2 Etiology.- 12.3 Initial or Repeated Episodes.- 12.4 Severity.- 12.5 Systemic Complications.- 12.6 Mortality.- 12.7 Late Morphological and Functional Consequences of the Pancreas.- 12.8 Quality of Life.- References.- 13 Chronic Pancreatitis: Etiology.- 13.1 Alcohol-induced Chronic Pancreatitis.- 13.2 Idiopathic Chronic Pancreatitis.- 13.3 Tropical Pancreatitis.- 13.4 Hereditary Diseases of the Pancreas.- 13.5 Congenital Abnormalities Including Pancreas Divisum.- 13.6 Obstructive Chronic Pancreatitis.- 13.7 Drug-induced Chronic Pancreatitis.- 13.8 Stress-induced Chronic Pancreatitis.- 13.9 Radiation-induced Chronic Pancreatitis.- 13.10 Hyperparathyroidism.- References.- 14 Chronic Pancreatitis: Pathophysiology.- 14.1 Concept of Primary Intraductal Obstruction.- 14.2 Concept of Primary Toxic-Metabolic Action of Alcohol.- 14.3 Concept of Oxidative Stress.- 14.4 Concept of Necrosis-Fibrosis Sequence.- References.- 15 Chronic Pancreatitis: Pathology.- 15.1 Gross Pathology.- 15.2 Histopathology.- 15.3 Chronic Pancreatitis With Focal Necrosis.- 15.4 Chronic Pancreatitis With Segmental or Diffuse Fibrosis.- 15.5 Obstructive Chronic Pancreatitis.- References.- 16 Chronic Pancreatitis: Epidemiology.- References.- 17 Chronic Pancreatitis: Diagnosis.- 17.1 Clinical Manifestation.- 17.2 Laboratory Inve