Description
Taylor & Francis Ltd Polymorphismj In Pharmaceutical Solids 2Nd Edition 2009 by Harry G. Brittain
Using clear and practical examples, Polymorphism of Pharmaceutical Solids, Second Edition presents a comprehensive examination of polymorphic behavior in pharmaceutical development that is ideal for pharmaceutical development scientists and graduate students in pharmaceutical science. This edition focuses on pharmaceutical aspects of polymorphism and solvatomorphism, while systematically explaining their thermodynamic and structural origins. Topics include:Computational methodologiesHigh-throughput screening methodsPharmaceutical cocrystalsThermally-induced and solution-mediated phase transformationsAmorphous solids Crystallography preparation and characterization The amorphous state THERMODYNAMIC AND THEORETICAL ISSUESTheory and Principles of Polymorphic Systems, Harry G. BrittainApplication of the Phase Rule to the Characterization of Polymorphic and Solvatomorphic Systems, Harry G. BrittainComputational Methodologies: Toward Crystal Structure and Polymorph Prediction, Sarah (Sally) L. PricePREPARATIVE METHODS FOR POLYMORPHS AND SOLVATOMORPHSClassical Methods of Preparation of Polymorphs and Alternative Solid Forms, Peter W. CainsApproaches to High-Throughput Physical Form Screening and Discovery, Alastair J. FlorenceSTRUCTURAL PROPERTIES OF POLYMORPHS AND SOLVATOMORPHSStructural Aspects of Polymorphism, Harry G. Brittain, Stephen R. Byrn, and Eunhee LeeStructural Aspects of Solvatomorphic Systems, Harry G. Brittain, Kenneth R. Morris, and Stephan X. M. BoerrigterPharmaceutical Co-crystals: A New Opportunity in Pharmaceutical Science for a Long-Known but Little-Studied Class of Compounds, Kapildev K. Arora and Michael J. ZaworotkoCHARACTERIZATION METHODS FOR POLYMORPHS AND SOLVATOMORPHSThermoanalytical and Crystallographic Methods, Sisir Bhattacharya, Harry G. Brittain, and Raj SuryanarayananVibrational Spectroscopy, Harry G. BrittainSolid-State Nuclear Magnetic Resonance Spectroscopy, Patrick A. TishmackEffects of Polymorphism and Solid-State Solvation on Solubility and Dissolution Rate, Harry G. Brittain, David J. R. Grant, and Paul B. MyrdalINTERCONVERSION OF POLYMORPHS AND SOLVATOMORPHSSolid-State Phase Transformations, Harry G. BrittainEffects of Pharmaceutical Processing on the Solid Form of Drug and Excipient Materials, Peter L. D. WildfongSPECIAL TOPICS RELATED TO POLYMORPHISM AND SOLVATOMORPHISMStructural Aspects of Molecular Dissymmetry, Harry G. BrittainAmorphous Solids, Lynne S. Taylor and Sheri L. ShamblinIndex