Description
Humana Press Portal Hypertension Pathobiology Evaluation And Treatment by Arun J. Sanyal , Vijay H. Shah
A cutting-edge review of the latest findings on key scientific topics and the best strategies for evaluation and management of portal hypertension in the clinic. Writing in an easy-to-read style, the authors review its pathobiology, the progress being made in its experimental understanding, the methodologies to assess it in humans, the treatment of its complications (esophageal varices, ascites, and hepatorenal syndrome), and its treatment in special circumstances (during pregnancy, in children, or when the portal vein is blocked). They also provide in-depth coverage of the pros and cons of the various therapeutic choices available to the clinician managing patients with complicated portal hypertension.show more Part I. Historical PerspectivePortal Hypertension: A HistoryAdrian Reuben and Roberto J. GroszmannPart II. Pathobiology and Experimental Progress in Portal HypertensionAnatomy and Vascular Biology of the Cells in the Portal CirculationMassimo Pinzani and Francesco VizzuttiCell and Molecular Mechanisms of Increased Intrahepatic Resistance and Hemodynamic CorrelatesDon C. RockeyMolecular Mechanisms of Systemic Vasodilation and Hyperdynamic Circulatory State of CirrhosisRichard Moreau and Didier LebrecMechanisms of Sodium Retention, Ascites Formation, and Renal Dysfunction in CirrhosisAndres Cardenas and Pere GinesHepatic Hemodynamics in Portal Hypertension: Compliance, Hepatic Arterial Buffer Response, Hepatorenal Syndrome, and Liver RegenerationW. Wayne Lautt and Zhi MingNeovascularization, Angiogenesis, and Vascular Remodeling in Portal HypertensionManuel Morales-Ruiz and Wladimiro JimenezMechanisms of Cardiopulmonary Hemodynamics and Dysfunction in Portal HypertensionMichael B. FallonPart III: Methodology to Assess Portal Hypertension in HumansMeasurement of Hepatic Venous Pressure Gradient: Methods, Interpretation, and PitfallsG. Pomier-Layrargues and P. Michel HuetEvaluation of Portal Hemodynamics Using Indicator Dilution and Noninvasive TechniquesJuerg ReichenEndoscopic Assessment of Portal Hypertension Including Variceal Pressure Measurements: Methods, Interpretation, and PitfallsAngels Escorsell and Jaime BoschPart IV: Natural History and Treatment of Esophageal VaricesClinical Features and Natural History of Variceal Hemorrhage: Implications for Surveillance and ScreeningJuan G. Abraldes and Jaime BoschManagement Strategies for the Prophylaxis and Treatment of Esophageal Variceal Rupture: AnOverviewRoberto de FranchisPharmacologic Therapy for the Management of Esophageal Varices: Biology and Utility of Available AgentsNorman D. Grace and Richard S. TilsonEndoscopic Treatment for Bleeding Esophageal VaricesJohn P. CelloSurgical Therapies for Management: Surgical Shunts and Liver TransplantationJ. Michael HendersonTransjugular Intrahepatic Portosystemic Stent-Shunt: Technical Considerations and Clinical Utility in the Management of Variceal HemorrhageDhiraj Tripathi, Peter C. Hayes, Doris N. Redhead, and Rajiv JalanClinical Features and Management of Gastric Varices, Portal Hypertensive Gastropathy, and Ectopic VaricesCharmaine A. Stewart and Patrick S. KamathPart V: Natural History and Treatment of Ascites and Hepatorenal SyndromeAscites: Clinical Features, Diagnosis, and Natural HistorySakib Karim Khalid and Guadalupe Garcia-TsaoManagement of AscitesFlorence WongSpontaneous Bacterial Peritonitis and Other Infections in CirrhosisRosa Maria Morillas and Ramon PlanasDiagnosis and Management of the Hepatorenal SyndromeKevin MoorePart V: Evaluation and Treatment in Special Circumstances of Portal HypertensionPregnancy and Portal HypertensionBimaljit Sandhu and Arun J. SanyalCauses and Management of Portal Hypertension in the Pediatric PopulationFrederick C. Ryckman, Maria H. Alonso, and Greg TiaoNoncirrhotic Portal Hypertension and Portal Vein ThrombosisShiv K. Sarin and Manav WadhawanHepatic Venous Outflow Obstruction: Budd-Chiari Syndrome and Veno-Occlusive Disease (Sinusoidal Obstruction Syndrome)Hugo E. Vargas and Thomas D. BoyerPulmonary Complications Associated with Portal HypertensionKaren L. Swanson and Michael J. KrowkaHealth Status Assessment and Economic An