Description
Springer Stem Cells and Cell Therapy by Mohamed Al-Rubeai, Mariam Naciri
With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells._x000D_ Table of contents : - _x000D_
Use of Human Embryonic Stem Cells in Therapy.- _x000D_
Human Neural Stem Cell-based Cell- and Gene-therapy for Neurological Diseases.- _x000D_
Vascular Stem Cell Therapy.- _x000D_
Bioprocessing of Human Pluripotent Stem Cells for Cell Therapy Applications.- _x000D_
Blood Cell Bioprocessing: The Haematopoietic System and Current Status of In-vitro Production of Red Blood Cells.- _x000D_
Bioprocessing Challenges Associated with the Purification of Cellular Therapies.- _x000D_
Separation Technologies for Stem Cell Bioprocessing._x000D_